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Research and Development

Research at the Department of Oncology and Medical Physics is more or less run in cooperation with other departments at the Hospital and also often together with different institutions.

​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​The global society ​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​​of cancer research is rather extensive and alive, and the acitivities are naturally quite resource intensive. Worldwide, all established Universities makes contributions to the field.
 

The activity is diverse and many groups work with translational research -  from basal problems to clinical applications. The Research groups Haukeland University Hosptial are multidisplinary but usually headed by a scientist with a medical background.

Collaboration
Mohn KreftforskingslaboratoriumME/CFS researchME patent (PDF) Particle therapy research


Publications

Publikasjoner ved Avdeling for kreftbehandling og medisinsk fysikk i 2014

Adjuvant radiotherapy in retroperitoneal sarcomas. A Scandinavian Sarcoma Group study of 97 patients. Trovik LH1, Ovrebo K, Almquist M, Haugland HK, Rissler P, Eide J, Engellau J, Monge OR, Nyhus AB, Elde IK, Jebsen NL.Publisert: Acta Oncol. 2014 Sep;53(9):1165-72. doi: 10.3109/0284186X.2014.921723. Epub 2014 Jul 7.

 

Anal carcinoma - Survival and recurrence in a large cohort of patienets treated according to Nordic guidelines. O Leon, M Guren, O Hagberg, B Glimelius, O Dahl, H Havsten, G Naucler, C Svenson, KM Tveit, A Jakobsen, P Pfeiffer, E Wanderås, T Ekman, B Lindh, L Baalteskard, G Frykholm, A Johnsson. Radiother Oncol 113:352-8, 2014.

 

Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer. Nik-Zainal, S., Wedge, D.C., Alexandrov, L., Petljak, M., Butler, A., Bolli, N., Davies, H.R., Knappskog, S., Martin, S., Papaemmanuil, E., Ramakrishna, M., Shlien, A., Simonic, I., Xue, Y., Tyler-Smith, C., Campbell, P.J. and Stratton, M.R. Nature Genetics. 46(5): 487-491, 2014.

 

Bilateral testicular germ cell tumors in patients treated for clinical stage I non.seminoma within two risk-adapted SWENOTECA protocols. T Tandstad, A Solberg, U Håkansson, O Stahl, HS Haugnes, J Oldenburg, O Dahl, A Kjellman, A Angelsen, G Crohn-Cedermark, Acta Oncol Online 5 sept. 2014.

 

Brakyterapi av malignt melanom i øyet. J Krohn, O DahlT Nybø, B Kjersem. Tidsskr nor legeforen 134:529, 2014.

 

Brachytherapy for malignant uveal melanoma. Krohn J, Dahl O,Nybø T, Kjersem B.   Tidsskr Nor Laegeforen. 2014 Mar 11;134(5):529.

 

CXCL12/CXCR ratio in colorectal cancer patients. L Stanisavljevic, J Assmus, O Dahl, MP

Myklebust EACR 23 BiennalCongress, Munchen 5-8 juli 2014.

 

Differences in metastatic patterns in relation to time between primary surgery and first relapse from breast cancer suggest synchronized growth of dormant micrometastasesDillekas H, Transeth M, Pilskog M, Assmus J, & Straume O (2014) Breast Cancer Res Treat 146(3):627-636.

 

DNA methylation status of key cell-cycle regulators such as CDKNA2/p16, CCND2 and CCNA1 correlates with treatment response to doxorubicin and 5-fluorouracil in locally advanced breast tumors.  Klajic J, Busato F, Edvardsen H, Touleimat N, Fleischer T, Bukholm I, Børresen-Dale A-L, Lønning PE, Tost J, Kristensen VN. Clin Cancer Res 20: 6357-66, 2014.

 

Effect of radium-223 dichloride on symptomatic skeletal events in patients with castration-resistant prostate cancer and bone metastases: results from a phase 3, double-blind, randomised trial. Sartor O, Coleman R, Nilsson S, Heinrich D, Helle SI, O'Sullivan JM, Fosså SD, Chodacki A, Wiechno P, Logue J, Widmark A, Johannessen DC, Hoskin P, James ND, Solberg A, Syndikus I, Vogelzang NJ, O'Bryan-Tear CG, Shan M, Bruland ØS, Parker C. Lancet Oncol. 2014 Jun;15(7):738-46. doi: 10.1016/S1470-2045(14)70183-4. Epub 2014 May 13.

 

Effects of SNP variants in the 17β-HSD2 and 17β-HSD7 genes and 17β-HSD7 copy number on gene transcript and estradiol levels in breast cancer tissueStraume AHKnappskog SLønning PE.  J Steroid Biochem Molec Biol 143C: 192-198, 2014.

 

Efficacy and safety of radium-223 dichloride in patients with castration-resistant prostate cancer and symptomatic bone metastases, with or without previous docetaxel use: a prespecified subgroup analysis from the randomised, double-blind, phase 3 ALSYMPCA trial. Hoskin P, Sartor O, O'Sullivan JM, Johannessen DC,Helle SI, Logue J, Bottomley D, Nilsson S, Vogelzang NJ, Fang F, Wahba M, Aksnes AK, Parker C. Lancet Oncol. 2014 Nov;15(12):1397-406. doi: 10.1016/S1470-2045(14)70474-7. Epub2014 Oct 17.

 

Estimated risk of radiation-induced cancer following paediatric cranio-spinal irradiation with electron, photon and proton therapy.Stokkevåg CHEngeseth GM, Ytre-Hauge KS, Röhrich D, Odland OH, Muren LP, Brydøy MHysing LB, Szostak A, Palmer MB, Petersen JB.  Acta Oncol. 2014 Aug;53(8): 1048-57.

 

Extensive transduction of non-repetitive DNA mediated by L1 retrotransposition in cancer genomes. Tubio, J.M.C., Li, Y., Ju, Y.S., Martincorena, I., Cooke. S., Tojo. M., Gundem, G., Pipinikas, C.P., Zamora, J., Raine, K., Menzies, A., Roman-Garcia, P., Gerstung, M., Shlien, A., Tarpey, P.S., Knappskog, S., Van Loo, P., Ramakrishna, M., Davies, H.R., Marshall, J., Wedge, D.C., Teague, J.W., Butler, A.P., Nik-Zainal, S., Behjati, S., Yates, L.R., Mudie, L., Hardy, C., Martin, S., ICGC Breast Cancer Group, ICGC Bone Cancer Group, ICGC Prostate Cancer Group, Foster, C., Warren, A.Y., Whitaker, H., Brewer, D., Eeles, R., Cooper, C., Neal, D., Lynch, A.G., Visakorpi, T., Isaacs, W.B., van 't Veer, L., Caldas, C., Desmedt, C., Sotiriou, C., Aparicio, S., Foekens, J., Eyfjörd, J.E., Lakhani, S.R.,  Thomas, G., Myklebost, O., Span, P., Børresen-Dale, A-L., Richardson, A.L., Flanagan, A.M., Futreal, A.P., Janes, S.M., Bova, G.S., Stratton, M.R., McDermott, U. and Campbell, P.J. Science. 345 (6196): 1251343-1 – 1251343-12, 2014.

 

Gastroenteropancreatic high-grade neuroendocrine carcinoma.Sorbye H, Strosberg J, Baudin E, Klimstra DS, Yao JC. Cancer. 2014 Sep 15;120(18):2814-23.

 

Impact of long-term serum platinum on neuro- and ototoxicity, cardiovascular disease, and hypogonadism in testicular cancer survivors . LV Hjelle, RM Bremnes, M Sprauten. M Brydøy, T Tandstad, SD Fosså, J Oldenburg. ASCO Annual Meeting, Juni 2014.

 

Management of clinical stage I seminomatous testicular cancer: A report from SWENOTECA.
T Tandstad, ECavallin-Stahl, O Dahl, Hs haugnes, CW Langberg, A Laurell, J Oldenburg, UK Stierner, A Solberg, K Søderström ASCO Annual Meeting juni 2014.

 

Interpreting plasma estrogen levels in breast cancer: caution needed.
Folkerd EJLønning PEDowsett M. J Clin Oncol 2014 May: 1396-1400, 2014.

 

Local recurrence rates after radiofrequency ablation or resection of colorectal liver metastases. Analysis of the European Organisation for Research and Treatment of Cancer #40004 and #40983. Tanis E, Nordlinger B, Mauer M, Sorbye H, van Coevorden F, Gruenberger T, Schlag PM, Punt CJ, Ledermann J, Ruers TJ.  Eur J Cancer. 2014 Mar;50 (5):912-9.

 

 

Longitudinal serum testosterone, luteinizing hormone, and follicle-stimulating hormone levels in a population-based sample of long-term testicular cancer survivors. Sprauten M, Brydøy M, Haugnes HS, Cvancarova M, Bjøro T, Bjerner J, Fosså SD, Oldenburg J. J Clin Oncol. 2014 Feb 20;32(6):571-8. doi: 10.1200/JCO.2013.51.2715. Epub 2014 Jan 13. PMID:24419125.

 

Modeling and validating the cost and clinical pathway of colorectal cancer. Joranger P, Nesbakken A, Hoff G, Sorbye H, Oshaug A, Aas E. Med Decis Making. 2015 Feb;35(2):255-65.

 

MDM2 SNP309 and risk of cervical cancer. (Letter to the Editor).Knappskog, S. and Lønning, P.E..Tumor Biology. 35:6185-6186, 2014.

 

MDM2 SNP309 and risk of endometrial cancer. (Letter to the Editor) .     Knappskog, S. and Lønning, P.E.Tumor Biology. 35:7285-7286, 2014.

 

Nestin expression is associated with aggressive cutaneous melanoma of the nodular type.

Ladstein RG, Bachmann IM, Straume O, & Akslen LA (2014) Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 27(3):396-401.

 

Nordic guidelines 2014 for diagnosis and treatment of gastroenteropancreatic neuroendocrine neoplasms. Janson ET,Sorbye H, Welin S, Federspiel B, Grønbæk H, Hellman P, Ladekarl M, Langer SW, Mortensen J, Schalin-Jäntti C, Sundin A, Sundlöv A, Thiis-Evensen E, Knigge U. Acta Oncol. 2014 Oct;53(10):1284-97.

 

Nuclear maspin expression as a predictive marker for fluouracil treatment response in colon cance rKE Hestetun, M Brydøy, MP Myklebust, O Dahl. Acta Oncol Online 17 sept. 2014.

 

One course of adjuvant BEP in clinical stage I nonseminoma. Mature and expanded results from the SWENOTECA group. T Tandstad, O Stahl, U Håkansson, O Dahl, HS Haugnes, OH Klepp, C Langberg, A Laurell, J Oldenburg, A Solberg, K Söderström, E Cavallin-Stahl, U Stierner; R Wahlquist, N Wall, G Cohn-Cedermark. Ann Oncol 25:2167-72, 2014.

 

Pelvic irradiation does not increase the risk of hip replacement in patients with gynecological cancer. A cohort study based on 8,507 patients. Dybvik E, Furnes O, Fosså SD, Trovik C, Lie SA. Acta Orthop. 2014 Dec;85(6):652-6. doi: 10.3109/17453674.2014.963784. Epub 2014 Sep 19. PMID:25238432] .

 

Plasma YKL-40 in patients with metastatic colorectal cancer treated with first line oxaliplatin-based regimen with or without cetuximab: RESULTS from the NORDIC VII Study. Tarpgaard LS, Guren TK, Glimelius B, Christensen IJ, Pfeiffer P, Kure EH, Sorbye H, Ikdahl T, Yilmaz M, Johansen JS, Tveit KM. PLoS One. 2014 Feb 3;9(2):e87746.

 

Plasma estrogens are elevated but in vivo aromatisation remains normal in postmenopausal overweight women.  Lønning PE, Haynes B, Dowsett M. Eur J Cancer 50: 1055-64, 2014.

 

Population Distribution and Ancestry of  the Cancer Protective MDM2 SNP285 (rs117039649)Knappskog SGansmo LB, Dibirova K, Metspalu A, Cybulski C, Peterlongo P,  Aaltonen L, Vatten L , Romundstad P, Hveem K, Devilee P,  Evans DG, Lin D, van Camp G, Manolopoulos E, Osorio A, Milani L, Ozcelik T,  Zalloua P, Mouzaya F, Zamora J, Wedge DC, Dörk T, Balanovsky O, Lønning PE. Oncotarget 5: 8223-34, 2014.

     

Prognostic role of en-bloc resection and late onset of bone metastasis in patients with bone-seeking carcinomas of the kidney, breast, lung, and prostate: SSG study on 672 operated skeletal metastases.   Ratasvuori M, Wedin R, Hansen BH, Keller J, Trovik C, Zaikova O, Bergh P, Kalen A, Laitinen M.  J Surg Oncol. 2014 May 29. doi: 10.1002/jso.23654. [Epub ahead of print].

 

Recurrence patterns after resection of liver metastases from colorectal cancerSorbye H. Recent Results Cancer Res. 2014;203:243-52.

 

Spontaneous reversion of the angiogenic phenotype to a nonangiogenic and dormant state in human tumors. Rogers MS, Novak K, Zurakowski D, Cryan LM, Blois A, Lifshits E, Bo TH, Oyan AM, Bender ER, Lampa M, Kang SY, Naxerova K, Kalland KH,Straume O, Akslen LA, Watnick RS, Folkman J, & Naumov GN (2014)Mol Cancer Res 12(5):754-764.

 

Status for protonterapi i NorgeOdd Harald Odland, Einar Waldeland, Anfinn Mehus og Jan Rødal;  Helse Medisin Teknikk, No 5, 2014.

 

Tannhelse ved bruk av bisfosfonater mot brystkreftEikesdal HP, Løes S, Herlofson BB. Tidsskr Nor Laegeforen. 2014;134:1451.

 

The emergence of targeted drugs in breast cancer to prevent resistance to endocrine treatment and chemotherapy. Austreid E,Lønning PEEikesdal HP. Exp Opin Pharmacother 15: 681-700, 2014.

 

The multitude of molecular analyses in cancer: the opening of Pandora's Box? Russnes HO, Lønning PE, Børresen-Dale A-L, Lingjærde OC. Genome Biology 15: art 447; s1-7, 2014.

 

The prognostic value of beta-catenin in anal cancer. H Jacob, O Dahl, MP MyklebustEACR 23 BiennialCongress, Munchen 5-8 juli 2014.

 

The total number of lymph nodes in resected colon cancer specimens is affected by several factors but the lymph node ratio is independent of these L Stanisavljevic, K Søndenaa, KE Storli, S Leh, I Nesvik, E Gudlaugsson, I Bukholm, GE Eide. APMIS 2014;122:490-8.

 

TP53 status predicts long-term survival in locally advanced breast cancer after primary chemotherapy .  Eikesdal HPKnappskog S, Aas T, Lønning PE. Acta Oncol 53: 1347-55, 2014.

 

Twenty-five years with adjuvant chemotherapy for colon cancer - a continous evolving conceptO Dahl, F Pfeffer. Acta Oncol 54:1-4, 2015.

Publikasjonar ved Avdeling for kreftbehandling og medisinsk fysikk i 2013.

1.Adaptive radiotherapy in locally advanced prostate cancer using a statistical deformable motion model.

Thörnqvist S, Hysing LB, Zolnay AG, Söhn M, Hoogeman MS, Muren LP, Heijmen BJ.

Acta Oncol. 2013 Oct;52(7):1423-9. doi: 10.3109/0284186X.2013.818249. Epub 2013 Aug 22.

PMID: 23964658

 

2. Age-dependent improvement in median and long-term survival in unselected population-based Nordic registries of patients with synchronous metastatic colorectal cancer.

Sorbye H, Cvancarova M, Qvortrup C, Pfeiffer P, Glimelius B.

Ann Oncol. 2013 Sep;24(9):2354-60. doi: 10.1093/annonc/mdt197. Epub 2013 May 22.

PMID:23704193

 

3.Alpha emitter radium-223 and survival in metastatic prostate cancer.

Parker C, Nilsson S, Heinrich D, Helle SI, O'Sullivan JM, Fosså SD, Chodacki A, Wiechno P, Logue J, Seke M, Widmark A, Johannessen DC, Hoskin P, Bottomley D, James ND, Solberg A, Syndikus I, Kliment J, Wedel S, Boehmer S, Dall'Oglio M, Franzén L, Coleman R, Vogelzang NJ, O'Bryan-Tear CG, Staudacher K, Garcia-Vargas J, Shan M, Bruland ØS, Sartor O; ALSYMPCA Investigators.

N Engl J Med. 2013 Jul 18;369(3):213-23. doi: 10.1056/NEJMoa1213755.

PMId:23863050

 

4.Aromatase inhibition 2013: clinical state of the art and questions that remain to be solved.

Lønning PE, Eikesdal HP.

Endocr Relat Cancer. 2013 Jun 24;20(4):R183-201. doi: 10.1530/ERC-13-0099. Print 2013 Aug. Review.

PMID:23625614

 

5.Continuation of bevacizumab after first progression in metastatic colorectal cancer (ML18147): a randomised phase 3 trial.

Bennouna J, Sastre J, Arnold D, Österlund P, Greil R, Van Cutsem E, von Moos R, Viéitez JM, Bouché O, Borg C, Steffens CC, Alonso-Orduña V, Schlichting C, Reyes-Rivera I, Bendahmane B, André T, Kubicka S; ML18147 Study Investigators.

Lancet Oncol. 2013 Jan;14(1):29-37. doi: 10.1016/S1470-2045(12)70477-1. Epub 2012 Nov 16.

PMID:23168366

 

6.CXXC5 (Retinoid-Inducible Nuclear Factor, RINF) is a Potential Therapeutic Target in High-Risk Human Acute Myeloid Leukemia

Astori A, Fredly H, Aloysius TA, Bullinger L, Mansat-De Mas, Grange P, Delhommeau F, Hagen KM, Recher C, Dusanter-Fourt I, Knappskog S, Lillehaug JR, Pendino F, Bruserud Ø.

Oncotarget. 2013 September; 4(9): 1438–1448. Published online 2013 August 15.

PMCID: PMC3824541

 

7.Diagnostic accuracy of dynamic gadoxetic-acid-enhanced MRI and PET/CT compared in patients with liver metastases from neuroendocrine neoplasms.

Armbruster M, Zech CJ, Sourbron S, Ceelen F, Auernhammer CJ, Rist C, Haug A, Singnurkar A, Reiser MF, Sommer WH.

J Magn Reson Imaging. 2013 Dec 18. doi: 10.1002/jmri.24363. [Epub ahead of print]

PMID:24347148

 

8.Diagnostic yield of biopsies of cervical lymph nodes using a large (14-gauge) core biopsy needle.

Pedersen OM, Aarstad HJ, Løkeland T, Bostad L.

APMIS. 2013 Mar 13. doi: 10.1111/apm.12058. [Epub ahead of print]

PMID:23489251

 

9.Degradation of target coverage due to inter-fraction motion during intensity-modulated proton therapy of prostate and elective targets.

Thörnqvist S, Muren LP, Bentzen L, Hysing LB, Høyer M, Grau C, Petersen JB.

Acta Oncol. 2013 Apr;52(3):521-7. doi: 10.3109/0284186X.2012.752860. Epub 2013 Feb 14.

PMID: 23409771

 

10.Differential inhibition of ex-vivo tumor kinase activity by vemurafenib in BRAF(V600E) and BRAF wild-type metastatic malignant melanoma.

Tahiri A, Røe K, Ree AH, deWijn R, Risberg K, Busch C, Lønning PE, Kristensen V, Geisler J.

PLoS One. 2013 Aug 30;8(8):e72692. doi: 10.1371/journal.pone.0072692. eCollection 2013.

PMID:24023633

 

11.Dose-densified chemoimmunotherapy followed by systemic central nervous system prophylaxis for younger high-risk diffuse large B-cell/follicular grade 3 lymphoma patients: results of a phase II Nordic Lymphoma Group study.

Holte H, Leppä S, Björkholm M, Fluge O, Jyrkkiö S, Delabie J, Sundström C, Karjalainen-Lindsberg ML, Erlanson M, Kolstad A, Fosså A, Ostenstad B, Löfvenberg E, Nordström M, Janes R, Pedersen LM, Anderson H, Jerkeman M, Eriksson M.

Ann Oncol. 2013 May;24(5):1385-92. doi: 10.1093/annonc/mds621. Epub 2012 Dec 17.

PMID:23247661

 

12.Dose/volume-response relations for rectal morbidity using planned and simulated motion-inclusive dose distributions.

Thor M, Apte A, Deasy JO, Karlsdóttir À, Moiseenko V, Liu M, Muren LP.

Radiother Oncol. 2013 Dec;109(3):388-93. doi: 10.1016/j.radonc.2013.10.021. Epub 2013 Nov 11.

PMID:24231236

 

13.Early rehabilitation of cancer patients - a randomized controlled intervention study.

Arving C, Thormodsen I, Brekke G, Mella O, Berntsen S, Nordin K.

BMC Cancer. 2013 Jan 7;13:9. doi: 10.1186/1471-2407-13-9.

PMID:23294513

 

14.Faecal incontinence after chemoradiotherapy in anal cancer survivors: long-term results of a national cohort.

Bentzen AG, Guren MG, Vonen B, Wanderås EH, Frykholm G, Wilsgaard T, Dahl O, Balteskard L.

Radiother Oncol. 2013 Jul;108(1):55-60. doi: 10.1016/j.radonc.2013.05.037. Epub 2013 Jul 25.

PMID:23891095

 

15.Functional characterisation of p53 mutants identified in breast cancers with suboptimal responses to anthracyclines or mitomycin.

Berge EO, Huun J, Lillehaug JR, Lønning PE, Knappskog S.

Biochim Biophys Acta. 2013 Mar;1830(3):2790-7.

PMID:23246812

 

16.Gamma knife surgery as monotherapy with clinically relevant doses prolongs survival in a human GBM xenograft model.

Sandvei BS, Wang J, Dodoo E, Heggdal JI, Grønli J, Sleire L, Bragstad S, Ganz JC, Chekenya M, Mørk S, Pedersen PH, Enger PØ.

Biomed Res Int. 2013;2013:139674. doi: 10.1155/2013/139674. Epub 2013 Nov 10.

PMID: 24312904 [PubMed - in process] Free PMC Article

 

17.Gamma knife surgery of colorectal brain metastases: a high prescription dose of 25 Gy may improve growth control.

Skeie BS, Enger PØ, Ganz JC, Skeie GO, Parr E, Hatteland S, Ystevik B, Heggdal JI, Pedersen PH.World Neurosurg. 2013 Mar-Apr;79(3-4):525-36. doi: 10.1016/j.wneu.2011.09.019. Epub 2012 Apr 16.

PMID: 22120263 [

 

18.High-dose therapy with autologous stem cell support for lymphoma--from experimental to standard treatment.

Smeland KB, Kiserud CE, Lauritzsen GF, Fosså A, Hammerstrøm J, Jetne V, Kolstad A, Kvalheim G, Loge JH, Løkeland T, Tangen JM, Holte H, Kvaløy S.

Tidsskr Nor Laegeforen. 2013 Sep 3;133(16):1735-9. doi: 10.4045/tidsskr.13.0319. English, Norwegian.

PMID:24005713

 

19.High-dose therapy with autologous stem cell support for lymphoma in Norway 1987-2008.

Smeland KB, Kiserud CE, Lauritzsen GF, Blystad AK, Fagerli UM, Fluge Ø, Fosså A, Hammerstrøm J, Kolstad A, Loge JH, Maisenhølder M, Østenstad B, Kvaløy S, Holte H.

Tidsskr Nor Laegeforen. 2013 Sep 3;133(16):1704-9. doi: 10.4045/tidsskr.13.0243. English, Norwegian.

PMID:24005706

 

20.Impaired health-related quality of life after chemoradiotherapy for anal cancer: late effects in a national cohort of 128 survivors.

Bentzen AG, Balteskard L, Wanderås EH, Frykholm G, Wilsgaard T, Dahl O, Guren MG.

Acta Oncol. 2013 May;52(4):736-44. doi: 10.3109/0284186X.2013.770599. Epub 2013 Feb 26.

PMID:23438358

 

21.Inverse regulation of EGFR/HER1 and HER2-4 in normal and malignant human breast tissue.

Flågeng MH, Knappskog S, Haynes BP, Lønning PE, Mellgren G.

PLoS One. 2013 Aug 22;8(8):e74618. doi: 10.1371/journal.pone.0074618. eCollection 2013.

PMID:23991224

 

22.Investigation of six testicular germ cell tumor susceptibility genes suggests a parent-of-origin effect in SPRY4.

Karlsson R, Andreassen KE, Kristiansen W, Aschim EL, Bremnes RM, Dahl O, Fosså SD, Klepp O, Langberg CW, Solberg A, Tretli S, Magnusson PK, Adami HO, Haugen TB, Grotmol T, Wiklund F.

Hum Mol Genet. 2013 Aug 15;22(16):3373-80. doi: 10.1093/hmg/ddt188. Epub 2013 May 2.

PMID:23640991

 

23.Is there a role for PET-CT and SPECT-CT in pediatric oncology?

Biermann M, Schwarzlmüller T, Fasmer KE, Reitan BC, Johnsen B, Rosendahl K.

Acta Radiol. 2013 Nov 1;54(9):1037-45. doi: 10.1258/ar.2012.120616. Epub 2013 Apr 30

PMID:23319723

 

24.Lapatinib in early breast cancer--questions to be resolved.

Lønning PE.

Lancet Oncol. 2013 Jan;14(1):11-2. doi: 10.1016/S1470-2045(12)70571-5. Epub 2012 Dec 10. No abstract available.

PMID:23234762

 

25.Lethal pneumonitis after docetaxel chemotherapy: case report and review of the literature.

Storaas E, Holmaas G, Gravdal K, Børretzen A, Eikesdal HP.

Acta Oncol. 2013 Jun;52(5):1034-8. doi: 10.3109/0284186X.2012.750734. Epub 2012 Dec 17. Review. No abstract available.

PMID:23244676

 

26.Low BRAF and NRAS expression levels are associated with clinical benefit from DTIC therapy and prognosis in metastatic melanoma.

Birkeland E, Busch C, Berge EO, Geisler J, Jönsson G, Lillehaug JR, Knappskog S, Lønning PE.

Clin Exp Metastasis. 2013 Oct;30(7):867-76. doi: 10.1007/s10585-013-9587-4. Epub 2013 May 15.

PMID:23673558

 

27.Malignant melanoma--diagnosis, treatment and follow-up in Norway.

Geisler J, Bachmann IM, Nyakas M, Helsing P, Fjøsne HE, Mæhle LO, Aamdal S, Eide NA, Svendsen HL, Straume O, Robsahm TE, Jacobsen KD, Akslen LA.

Tidsskr Nor Laegeforen. 2013 Oct 29;133(20):2154-9. doi: 10.4045/tidsskr.12.1416. Review. English, Norwegian.

PMID:24172628

 

28.Mapping genetic alterations causing chemoresistance in cancer: identifying the roads by tracking the drivers.

Lønning PE, Knappskog S.

Oncogene. 2013 Nov 14;32(46):5315-30. doi: 10.1038/onc.2013.48. Epub 2013 Mar 11. Review.

PMID:23474753

 

29.MDM2 SNP309 and risk of endometrial cancer.

Knappskog S, Lønning PE.

Pol J Pathol. 2013 Apr;64(1):69-70. No abstract available.

PMID:23625604

 

30. Measurements and Monte Carlo Simulations of Neutron Doses from Radiation Therapy with Photons, Protons and Carbon Ions.

Dec. 10, 2013

Kristian S. Ytre-Hauge

Doktorgradsavhandling UiB.

 

31.Nestin expression is associated with aggressive cutaneous melanoma of the nodular type.

Ladstein RG, Bachmann IM, Straume O, Akslen LA.

Mod Pathol. 2014 Mar;27(3):396-401. doi: 10.1038/modpathol.2013.151. Epub 2013 Sep 13.

PMID:24030749

 

32.Patterns of local recurrence and dose fractionation of adjuvant radiation therapy in 462 patients with soft tissue sarcoma of extremity and trunk wall.

Jebsen NL, Engellau J, Engström K, Bauer HC, Monge OR, Muren LP, Eide GE, Trovik CS, Bruland OS.

Int J Radiat Oncol Biol Phys. 2013 Aug 1;86(5):949-55. doi: 10.1016/j.ijrobp.2013.04.015. Epub 2013 May 29.

PMID:23725998

 

33.Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial.

Nordlinger B, Sorbye H, Glimelius B, Poston GJ, Schlag PM, Rougier P, Bechstein WO, Primrose JN, Walpole ET, Finch-Jones M, Jaeck D, Mirza D, Parks RW, Mauer M, Tanis E, Van Cutsem E, Scheithauer W, Gruenberger T; EORTC Gastro-Intestinal Tract Cancer Group; Cancer Research UK; Arbeitsgruppe Lebermetastasen und–tumoren in der Chirurgischen Arbeitsgemeinschaft Onkologie (ALM-CAO); Australasian Gastro-Intestinal Trials Group (AGITG); Fédération Francophone de Cancérologie Digestive (FFCD).

Lancet Oncol. 2013 Nov;14(12):1208-15. doi: 10.1016/S1470-2045(13)70447-9. Epub 2013 Oct 11.

PMID:24120480

 

34.Prediction of rectum and bladder morbidity following radiotherapy of prostate cancer based on motion-inclusive dose distributions.

Thor M, Bentzen L, Hysing LB, Ekanger C, Helle SI, Karlsdóttir Á, Muren LP.

Radiother Oncol. 2013 May;107(2):147-52. doi: 10.1016/j.radonc.2013.03.029. Epub 2013 May 14.

PMID:23684586

 

35.Predictive and prognostic factors for treatment and survival in 305 patients with advanced gastrointestinal neuroendocrine carcinoma (WHO G3): the NORDIC NEC study.

Sorbye H, Welin S, Langer SW, Vestermark LW, Holt N, Osterlund P, Dueland S, Hofsli E, Guren MG, Ohrling K, Birkemeyer E, Thiis-Evensen E, Biagini M, Gronbaek H, Soveri LM, Olsen IH, Federspiel B, Assmus J, Janson ET, Knigge U.

Ann Oncol. 2013 Jan;24(1):152-60

PMID:22967994

 

36.Pseudoprogression in high-grade glioma.

Knudsen-Baas KM, Moen G, Fluge Ø, Storstein A.

Acta Neurol Scand Suppl. 2013;(196):31-7. doi: 10.1111/ane.12047. Review. Erratum in: Acta Neurol Scand Suppl. 2013 Mar;127(3):e17.

PMID:23190289

 

37.Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors.

Klajic J, Fleischer T, Dejeux E, Edvardsen H, Warnberg F, Bukholm I, Lønning PE, Solvang H, Børresen-Dale AL, Tost J, Kristensen VN.

BMC Cancer. 2013 Oct 5;13:456. doi: 10.1186/1471-2407-13-456.

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38. Signatures of mutational processes in human cancer

Alexandrov LB, Nik-Zainal S, Wedge DC,….Knappskog S et al:

Nature. 2013 August 22; 500(7463): 415–421. Published online 2013 August 14. doi: 10.1038/nature12477

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40.Treatment simulations with a statistical deformable motion model to evaluate margins for multiple targets in radiotherapy for high-risk prostate cancer.

Thörnqvist S, Hysing LB, Zolnay AG, Söhn M, Hoogeman MS, Muren LP, Bentzen L, Heijmen BJ.

Radiother Oncol. 2013 Dec;109(3):344-9. doi: 10.1016/j.radonc.2013.09.012. Epub 2013 Oct 31.

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41.Tumor vasculature: the Achilles' heel of cancer?

Johannessen TC, Wagner M, Straume O, Bjerkvig R, Eikesdal HP.

Expert Opin Ther Targets. 2013 Jan;17(1):7-20. doi: 10.1517/14728222.2013.730522. Epub 2012 Nov 2. Review.

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42.Vascular proliferation is associated with survival in pancreatic ductal adenocarcinoma.

Hoem D, Straume O, Immervoll H, Akslen LA, Molven A.

APMIS. 2013 Nov;121(11):1037-46. doi: 10.1111/apm.12057. Epub 2013 Mar 13.

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1.Bentzen, Anne Gry; Guren, Marianne; Wanderås, Eva Hoff; Frykholm, Gunilla; Tveit, Magne Kjell; Wilsgaard, Tom; Dahl, Olav; Balteskard, Lise.

Chemoradiotherapy of Anal Carcinoma: Survival and Recurrence in an Unselected National Cohort. International Journal of Radiation Oncology, Biology, Physics 2012 ;Volum 83.(2) s. E173-E180

HAUKELAND HN OUS STO UiB UiO UiT UNN

  

 

2.  Tveit, Magne Kjell; Guren, Tormod Kyrre; Glimelius, Bengt; Pfeiffer, Per; Sorbye, Halfdan; Pyrhonen, Seppo; Sigurðsson, Friðbjörn; Kure, Elin H.; Andersen, Tone Ikdahl; Skovlund, Eva; Fokstuen, Tone; Hansen, Flemming; Hofsli, Eva; Birkemeyer, Elke; Johnsson, Anders; Starkhammar, Hans; Yilmaz, Mette Karen; Keldsen, Nina; Erdal, Anne Berit Rødal; Dajani, Olav; Dahl, Olav; Christoffersen, Thoralf.

Phase III trial of cetuximab with continuous or intermittent fluorouracil, leucovorin, and oxaliplatin (Nordic FLOX) versus FLOX alone in first-line treatment of metastatic colorectal cancer: The NORDIC-VII Study. Journal of Clinical Oncology 2012 ;Volum 30.(15) s. 1755-1762

HAUKELAND OUS STO SUS UiB UiO

  

 

3.  Arnes, Jarle; Stefansson, Ingunn Marie; Straume, Oddbjørn; Baak, Jan P.A.; Lønning, Per Eystein; Foulkes, William D.; Akslen, Lars A..

Vascular proliferation is a prognostic factor in breast cancer. Breast Cancer Research and Treatment 2012 ;Volum 133.(2) s. 501-510

HAUKELAND SUS UiB

  

 

4.  Bell, Rae Frances; Borzan, Jasenka; Kalso, Eija; Simonnet, Guy.

Food, pain, and drugs: Does it matter what pain patients eat?. Pain 2012 ;Volum 153.(10) s. 1993-1996

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5.  Bell, Rae Frances; Eccleston, C hristopher; Kalso, Eija A..

Ketamine as an adjuvant to opioids for cancer pain. Cochrane Database of Systematic Reviews 2012 (11:CD003351) s. -

HAUKELAND

  

 

6.  Bergh, Irmelin; Aass, Nina Kathrine; Haugen, Dagny Faksvåg; Kaasa, Stein; Hjermstad, Marianne Jensen.

Symptomkartlegging i palliativ medisin. Tidsskrift for Den norske legeforening 2012 ;Volum 132. s. 18-19

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7.  Bjørnslett, Merete Pauline; Knappskog, Stian; Lønning, Per Eystein; Dørum, Anne.

Effect of the MDM2 promoter polymorphisms SNP309T>G and SNP285G>C on the risk of ovarian cancer in BRCA1 mutation carriers. BMC Cancer 2012 ;Volum 12. s. -

HAUKELAND OUS UiB UiO

  

 

8.  Bliss, Judith M.; Kilburn, Lucy S.; Coleman, Robert E.; Forbes, John F.; Coates, Alan S.; Jones, Stephen E.; Jassem, Jacek; Delozier, Thierry; Andersen, Jørn; Paridaens, Robert; Van de Velde, Cornelis J.H.; Lønning, Per Eystein; Morden, James; Reise, Justine; Cisar, Laura; Menschik, Thomas; Coombes, R. Charles.

Disease-related outcomes with long-term follow-up: an updated analysis of the intergroup exemestane study. Journal of Clinical Oncology 2012 ;Volum 30.(7) s. 709-717

HAUKELAND UiB

  

 

9.  Brydøy, Marianne; Fosså, Sophie Dorothea; Klepp, Olbjørn; Bremnes, Roy M.; Wist, Erik; Bjøro, Trine; Wentzel-Larsen, Tore; Dahl, Olav.

Sperm counts and endocrinological markers of spermatogenesis in long-term survivors of testicular cancer. British Journal of Cancer 2012 ;Volum 107.(11) s. 1833-1839

HAUKELAND NKVTS NTNU OUS RBUP-ØS STO UiB UiO UiT UNN

  

 

10.  Cao, Maria Dung; Döpkens, Mailin; Krishnamachary, Balaji; Vesuna, Farhad; Gadiya, Mayur M.; Lønning, Per Eystein; Bhujwalla, Zaver M.; Gribbestad, Ingrid S; Glunde, Kristine.

Glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) expression correlates with malignant choline phospholipid metabolite profiles in human breast cancer. NMR in Biomedicine 2012 ;Volum 25.(9) s. 1033-1042

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11.  Cao, Maria Dung; Giskeødegård, Guro F.; Bathen, Tone Frost; Sitter, Beathe; Bofin, Anna M.; Lønning, Per Eystein; Lundgren, Steinar; Gribbestad, Ingrid S.

Prognostic value of metabolic response in breast cancer patients receiving neoadjuvant chemotherapy. Kongsvold møte; 2012-08-29 - 2012-08-30

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12.  Cao, Maria Dung; Giskeødegård, Guro F.; Bathen, Tone Frost; Sitter, Beathe; Bofin, Anna M.; Lønning, Per Eystein; Lundgren, Steinar; Gribbestad, Ingrid S.

Prognostic value of metabolic response in breast cancer patients receiving neoadjuvant chemotherapy. BMC Cancer 2012 ;Volum 12. s. -

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13.  Cao, Maria Dung; Sitter, Beathe; Bathen, Tone Frost; Bofin, Anna M.; Lønning, Per Eystein; Lundgren, Steinar; Gribbestad, Ingrid S.

Predicting long-term survival and treatment response in breast cancer patients receiving neoadjuvant chemotherapy by MR metabolic profiling. NMR in Biomedicine 2012 ;Volum 25.(2) s. 369-378

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14.  Caraceni, Augusto; Hanks, Geoffrey; Kaasa, Stein; Bennett, Michael I; Brunelli, C; Cherny, Nathan; Dale, Ola; De Conno, Franco; Fallon, M; Hanna, M; Haugen, Dagny Faksvåg; Juhl, Gitte Irene; King, S.; Klepstad, Pål; Laugsand, Eivor Alette; Maltoni, M; Mercadante, S.; Nabal, M; Pigni, Alessandra; Radbruch, L; Reid, C; Sjogren, Per; Stone, Patrick; Tassinari, D; Zeppetella, G.

Use of opioid analgesics in the treatment of cancer pain: evidence-based recommendations from the EAPC. The Lancet Oncology 2012 ;Volum 13.(2) s. E58-E68

HAUKELAND NTNU STO

  

 

  

 

15.  Cavalli-Björkman, Nina; Qvortrup, Camilla; Sebjørnsen, Sigrunn; Pfeiffer, Per; Wentzel-Larsen, Tore; Glimelius, Bengt; Sorbye, Halfdan.

Lower treatment intensity and poorer survival in metastatic colorectal cancer patients who live alone. British Journal of Cancer 2012 ;Volum 107.(1) s. 189-194

HAUKELAND NKVTS RBUP-ØS

  

 

16.  Dahl, Olav; Brydøy, Marianne.

Testicular germ cell tumours - still many challenges. Acta Oncologica 2012 ;Volum 51.(2) s. 147-150

HAUKELAND UiB

  

 

  

 

17.  Fassnacht, Martin; Terzolo, Massimo; Allolio, Bruno; Baudin, Eric; Haak, Harm; Berruti, Alfredo; Welin, Staffan; Schade-Brittinger, Carmen; Lacroix, André; Jarzab, Barbara; Sorbye, Halfdan; Torpy, David J.; Stepan, Vinzenz; Schteingart, David E.; Arlt, Wiebke; Kroiss, Matthias; Leboulleux, Sophie; Sperone, Paola; Sundin, Anders; Hermsen, Ilse; Hahner, Stefanie; Willenberg, Holger S.; Tabarin, Antoine; Quinkler, Marcus; de la Fouchardiere, Christelle; Schlumberger, Martin; Mantero, Franco; Weismann, Dirk; Beuschlein, Felix; Gelderblom, Hans; Wilmink, Hanneke; Sender, Monica; Edgerly, Maureen; Kenn, Werner; Fojo, Tito; Müller, Hans-Helge; Skogseid, Britt.

Combination Chemotherapy in Advanced Adrenocortical Carcinoma. New England Journal of Medicine 2012 ;Volum 366.(23) s. 2189-2197

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18.  Flågeng, Marianne Hauglid; Larionov, Alexey; Geisler, Jürgen; Dixon, JM; Lønning, Per Eystein; Mellgren, Gunnar.

Inverse regulation of Neuregulin 1 and HER-3 during treatment with aromatase inhibitors of estrogen receptor-positive breast cancer. San Antonio Breast Cancer Symphosium; 2012-12-04 - 2012-12-08

AHUS HAUKELAND UiB

  

 

19.  Gomes, B; Higginson, IJ; Calanzani, N; Cohen, J; Deliens, L; Daveson, BA; Bechinger-English, D; Bausewein, C; Ferreira, PL; Toscani, F; Menaca, A; Gysels, M; Ceulemans, L; Simon, ST; Pasman, HRW; Albers, G; Hall, S; Murtagh, FEM; Haugen, Dagny Faksvåg; Downing, J; Koffman, J; Pettenati, F; Finetti, S; Antunes, B; Harding, R.

Preferences for place of death if faced with advanced cancer: a population survey in England, Flanders, Germany, Italy, the Netherlands, Portugal and Spain. Annals of Oncology 2012 ;Volum 23.(8) s. 2006-2015

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20.  Haugen, Dagny Faksvåg; Sigurdardottir, Katrin Rut.

Medikamentskrin for symptomlindring i livets sluttfase.. Utposten 2012 ;Volum 41.(1) s. 36-36

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21.  Haugnes, Hege Sagstuen; Bosl, Geroge J; Boer, Hink; Gietema, Jourik A.; Brydøy, Marianne; Oldenburg, Jan; Dahl, Alv A; Bremnes, Roy M.; Fosså, Sophie Dorothea.

Long Term and Late Effects of Germ Cell Testicular Cancer Treatment and Implications for Follow-Up.. Journal of Clinical Oncology 2012 ;Volum 30.(30) s. 3752-3763

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22.  Haugnes, Hege Sagstuen; Laurell, Anna; Stierner, Ulrika; Bremnes, Roy M.; Dahl, Olav; Cavallin-Ståhl, Eva; Cohn-Cedermark, Gabriella.

High-dose chemotherapy with autologous stem cell support in patients with metastatic non-seminomatous testicular cancer - a report from the Swedish Norwegian Testicular Cancer Group (SWENOTECA). Acta Oncologica 2012 ;Volum 51.(2) s. 168-176

HAUKELAND UiB UiT UNN

   

 

  

 

23.  Hjermstad, Marianne Jensen; Lie, Hanne Cathrine; Caraceni, Augusto; Currow, David; Fainsinger, Robin; Gundersen, Odd Erik; Haugen, Dagny Faksvåg; Heitzer, Ellen; Radbruch, Lukas; Stone, Patrick; Strasser, Florian; Kaasa, Stein; Loge, Jon Håvard.

Computer-Based Symptom Assessment Is Feasible in Patients With Advanced Cancer: Results From an International Multicenter Study, the EPCRC-CSA. Journal of Pain Symptom and Management 2012 ;Volum 44.(5) s. 639-654

HAUKELAND NTNU OUS STO UiO

  

 

24.  Jansson, Ragnhild Wivestad; Frøystein, Torbjørn; Krohn, Jørgen Gitlesen.

Topographical distribution of retinal and optic disc neovascularization in early stages of proliferative diabetic retinopathy. Investigative Ophthalmology and Visual Science 2012 ;Volum 53.(13) s. 8246-8252

HAUKELAND UiB

  

 

  

 

25.  Joensuu, Heikki; Eriksson, Mikael; Hall, Kirsten Sundby; Hartmann, Jörg T.; Pink, Daniel; Schütte, Jochen; Ramadori, Giuliano; Hohenberger, Peter; Duyster, Julius; Al-Batran, Salah-Eddin; Schlemmer, Marcus; Bauer, Sebastian; Wardelmann, Eva; Sarlomo-Rikala, Maarit; Nilsson, Bengt; Sihto, Harri; Monge, Odd R; Bono, Petri; Kallio, Raija; Vehtari, Aki; Leinonen, Mika; Alvegård, Thor; Reichardt, Peter.

One vs three years of adjuvant imatinib for operable gastrointestinal stromal tumor : a randomized trial. Journal of the American Medical Association (JAMA) 2012 ;Volum 307.(12) s. 1265-1272

HAUKELAND OUS

  

 

  

 

26.  Karlsson, Robert; Kristiansen, Wenche; Andreassen, Kristine Engen; Aschim, Elin Leirvoll; Bremnes, Roy M.; Dahl, Olav; Fosså, Sophie Dorothea; Klepp, Olbjørn; Langberg, Carl W.; Solberg, Arne; Tretli, Steinar; Magnusson, Patrik K.E.; Adami, Hans-Olov; Haugen, Trine Berit; Grotmol, Tom; Wiklund, Fredrik.

Validation, fine-mapping, and characterization of six genes related to testicular germ cell tumour in a large Swedish-Norwegian population. 7th European Congress of Andrology; 2012-11-28 - 2012-12-01

HAUKELAND HIOA HSM KREFTREG NTNU OUS UiT

  

 

27.  Knappskog, Stian; Chrisanthar, Ranjan; Løkkevik, Erik; Anker, Gun Birgitta; Østenstad, Bjørn; Lundgren, Steinar; Risberg, Terje; Mjaaland, Ingvil; Leirvaag, Beryl; Miletic, Hrvoje; Lønning, Per Eystein.

Low expression levels of ATM may substitute for CHEK2/TP53 mutations predicting resistance towards anthracycline and mitomycin chemotherapy in breast cancer. Breast Cancer Research 2012 ;Volum 14.(2:R47) s. -

HAUKELAND NTNU OUS STO SUS UiB UiT UNN

  

 

28.  Knappskog, Stian; Gansmo, Liv Beathe; Romundstad, Pål Richard; Bjørnslett, Merete Pauline; Trovik, Jone; Sommerfelt-Pettersen, Jan; Løkkevik, Erik; Tollenaar, Rob A.E.M.; Seynaeve, Caroline; Devilee, Peter; Salvesen, Helga Birgitte; Dørum, Anne; Hveem, Kristian; Vatten, Lars Johan; Lønning, Per Eystein.

MDM2 Promoter SNP344T>A (rs1196333) Status Does Not Affect Cancer Risk. PLoS ONE 2012 ;Volum 7.(4) s. -

HAUKELAND NTNU OUS UiB UiO

  

 

29.  Knappskog, Stian; Lønning, Per Eystein.

P53 and its molecular basis to chemoresistance in breast cancer. Expert opinion on therapeutic targets 2012 ;Volum 16. s. S23-S30

HAUKELAND UiB

  

 

30.  Knappskog, Stian; Trovik, Jone; Marcickiewicz, Janusz; Tingulstad, Solveig; Staff, Anne Cathrine; Romundstad, Pål Richard; Hveem, Kristian; Vatten, Lars Johan; Salvesen, Helga Birgitte; Lønning, Per Eystein.

SNP285C modulates oestrogen receptor/Sp1 binding to the MDM2 promoter and reduces the risk of endometrial but not prostatic cancer. European Journal of Cancer 2012 ;Volum 48.(13) s. 1988-1996

HAUKELAND NTNU OUS STO UiB UiO

  

 

31.  Knudsen, Anne Kari; Klepstad, Pål; Brunelli, C; Aas, Nina; Haugen, Dagny Faksvåg; Caraceni, Augusto; Kaasa, Stein.

Detecting key domains for cancer pain classification.. World Congress of the European Association for palliative care (EAPC); 2012-06-07 - 2012-06-09

HAUKELAND NTNU

  

 

32.  Kristiansen, Wenche; Andreassen, Kristine Engen; Karlsson, Robert; Aschim, Elin Leirvoll; Bremnes, Roy M.; Dahl, Olav; Fosså, Sophie Dorothea; Klepp, Olbjørn; Langberg, Carl W.; Solberg, Arne; Tretli, Steinar; Adami, Hans-Olov; Wiklund, Fredrik; Grotmol, Tom; Haugen, Trine Berit.

Gene variations in sex hormone pathways and the risk of testicular germ cell tumour: A case-parent triad study in a Norwegian-Swedish population. 17th European Workshop on Molecular and Cellular Endocrinology of the Testis; 2012-04-20 - 2012-04-24

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33.  Kristiansen, Wenche; Andreassen, Kristine Engen; Karlsson, Robert; Aschim, Elin Leirvoll; Bremnes, Roy M.; Dahl, Olav; Fosså, Sophie Dorothea; Klepp, Olbjørn; Langberg, Carl W.; Solberg, Arne; Tretli, Steinar; Adami, Hans-Olov; Wiklund, Fredrik; Grotmol, Tom; Haugen, Trine Berit.

Gene variations in sex hormone pathways and the risk of testicular germ cell tumour: a case-parent triad study in a Norwegian-Swedish population. Human Reproduction 2012 ;Volum 27.(5) s. 1525-1535

HAUKELAND HIOA HSM KREFTREG OUS STO UiB UiO UiT UNN

  

 

34.  Ladstein, Rita Grude; Bachmann, Ingeborg M.; Straume, Oddbjørn; Akslen, Lars A..

Prognostic Importance of the Mitotic Marker Phosphohistone H3 in Cutaneous Nodular Melanoma. Journal of Investigative Dermatology 2012 ;Volum 132.(4) s. 1247-1252

HAUKELAND UiB

  

 

35.  Ladstein, Rita Grude; Bachmann, Ingeborg M.; Straume, Oddbjørn; Akslen, Lars A..

Tumor necrosis is a prognostic factor in thick cutaneous melanoma. American Journal of Surgical Pathology 2012 ;Volum 36.(10) s. 1477-1482

HAUKELAND UiB

  

 

  

 

36.  Miller, K.; Sartor, AO; Heinrich, Daniel; Helle, Svein Inge; O'Sullivan, JM; Fossa, S. D.; Chodacki, A.; Demkow, T.; Logue, JP; Seke, M.; Widmark, A; Johannessen, D.C.; Nilsson, S.; Hoskin, P.; Solberg, Arne; James, ND; Syndikus, I.; Vogelzang, Nicholas J; O'Bryan-Tear, CG; Shan, M.; Parker, C.

Radium-223 chloride impact on skeletal-related events in patients with castration-resistant prostate cancer (CRPC) with bone metastases: A phase III randomized trial (ALSYMPCA). Onkologie (Basel) 2012 ;Volum 35. s. 238-239

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37.  Moore, Andrew; McQuay, Henry; Wiffen, Phil; Derry, Sheena; Straube, Sebastian; Eccleston, Christopher; Bell, Rae Frances; Aldington, Dominic; Phillips, Ceri.

Estimate at your peril: Imputation methods for patient withdrawal can bias efficacy outcomes in chronic pain trials using responder analyses Response. Pain 2012 ;Volum 153.(7) s. 1541-1542

HAUKELAND

  

 

38.  Moore, R. Andrew; Straube, Sebastian; Eccleston, Christopher; Derry, Sheena; Aldington, Dominic; Wiffen, Philip; Bell, Rae Frances; Hamunen, Katri; Phillips, Ceri; McQuay, Henry.

Estimate at your peril: Imputation methods for patient withdrawal can bias efficacy outcomes in chronic pain trials using responder analyses. Pain 2012 ;Volum 153.(2) s. 265-268

HAUKELAND

  

 

39.  Myklebust, Mette Pernille; Fluge, Øystein; Immervoll, Heike; Skarstein, Arne; Balteskard, Lise; Bruland, Ove; Dahl, Olav.

Expression of DSG1 and DSC1 are prognostic markers in anal carcinoma patients. British Journal of Cancer 2012 ;Volum 106.(4) s. 756-762

HAUKELAND UiB UNN

  

 

40.  Myklebust, Mette Pernille; Li, Zhiping; Tran, Thai H.; Rui, Hallgeir; Knudsen, Erik S.; Elsaleh, Hany; Fluge, Øystein; Vonen, Barthold; Myrvold, Helge Elliot; Leh, Sabine; Tveit, Magne Kjell; Pestell, Richard G.; Dahl, Olav.

Expression of cyclin D1a and D1b as predictive factors for treatment response in colorectal cancer. British Journal of Cancer 2012 ;Volum 107.(10) s. 1684-1691

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41.  Nordlinger, Bernard; Sorbye, Halfdan; Glimelius, Bengt; Poston, Graeme John; Schlag, Peter M.; Rougier, Philippe; Bechstein, Wolf O.; Primrose, John N.; Walpole, Euan Thomas; Finch-Jones, Meg; Jaeck, Daniel; Mirza, Darius; Parks, Rowan W.; Collette, Laurence; Praet, Michel; Van Cutsem, Eric; Scheithauer, Werner; Mauer, Murielle E.; Gruenberger, Thomas.

Long term survival data from EORTC Study 40983: perioperative chemotherapy for resectable liver metastases from colorectal cancer. Annals of Oncology 2012 ;Volum 23. Suppl. 4 s. 18-18

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42.Parker, C; Heinrich, D.; Helle, Svein Inge; O'Sullivan, JM; Fossa, S.; Chodacki, A.; Demkow, T.; Logue, J.; Seke, M.; Widmark, A; Johannessen, Dag Clement; Nilsson, S.; Hoskin, P.; Bottomley, D.; Solberg, Arne; James, ND; Syndikus, I.; Wedel, S.A.; Kliment, J.; Cross, A; O'Bryan-Tear, CG; Garcia-Vargas, J.; Sartor, O..

Overall survival benefit and impact on skeletal-related events for radium-223 chloride (Alpharadin) in the treatment of castration-resistant prostate cancer (CRPC) patients with bone metastases: A phase III randomized trial (ALSYMPCA). European urology. Supplement 2012 ;Volum 11.(1) s. E130-U523

HAUKELAND OUS STO

  

 

43.  Qvortrup, C; Cvancarova, M; Glimelius, B.; Pfeiffer, P; Sorbye, Halfdan.

AGE DEPENDENT INCREASE IN MEDIAN AND LONG-TERM SURVIVAL IN 29 628 METASTATIC COLORECTAL CANCER (MCRC) SCANDINAVIAN PATIENTS DURING THE PAST TWO DECADES. Annals of Oncology 2012 ;Volum 23. s. 188-188

HAUKELAND KREFTREG UiO

  

 

44.  Rades, Dirk; Setter, Cornelia; Dahl, Olav; Schild, Steven E.; Noack, Frank.

Fibroblast growth factor 2—A predictor of outcome for patients irradiated for stage II-III non–small-cell lung cancer. International Journal of Radiation Oncology, Biology, Physics 2012 ;Volum 82.(1) s. 442-447

HAUKELAND UiB

  

 

45.  Rades, Dirk; Setter, Cornelia; Dahl, Olav; Schild, Steven E.; Noack, Frank.

The prognostic impact of tumor cell expression of estrogen receptor-alpha, progesterone receptor, and androgen receptor in patients irradiated for nonsmall cell lung cancer. Cancer 2012 ;Volum 118.(1) s. 157-163

HAUKELAND UiB

  

 

46.  Ries, Anke; Trottenberg, Peter; Elsner, Frank; Stiel, Stephanie; Haugen, Dagny Faksvåg; Kaasa, Stein; Radbruch, Lukas.

A systematic review on the role of fish oil for the treatment of cachexia in advanced cancer: An EPCRC cachexia guidelines project. Palliative Medicine : A Multiprofessional Journal 2012 ;Volum 26.(4) s. 294-304

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47.  Riihijärvi, Sari; Nurmi, Heidi; Holte, Harald; Björkholm, Magnus; Fluge, Øystein; Pedersen, Lars Møller; Rydström, Karin; Jerkeman, Mats; Eriksson, Mikael; Leppä, Sirpa.

High serum vascular endothelial growth factor level is an adverse prognostic factor for high-risk diffuse large B-cell lymphoma patients treated with dose-dense chemoimmunotherapy. European Journal of Haematology 2012 ;Volum 89.(5) s. 395-402

HAUKELAND OUS

  

 

48.  Roy, Arunabha; Cunningham, David; Hawkins, Robert; Sorbye, Halfdan; Adenis, Antoine; Barcelo, Jose Ramon; Lopez-Vivanco, Guillermo; Adler, Guido; Canon, Jean-Luc; Lofts, Fiona; Castanon, C.; Fonseca, E.; Rixe, Olivier; Aparicio, Jorge; Cassinello, Javier; Nicolson, Marianne; Mousseau, Mireille; Schalhorn, Andreas; D'Hondt, Lionel; Kerger, Joseph; Hossfeld, Dieter K.; García-Girón, Carlios; Rodriguez, R.; Schöffski, Patrick; Misset, Jean-Louis.

Docetaxel combined with irinotecan or 5-fluorouracil in patients with advanced oesophago-gastric cancer: a randomised phase II study. British Journal of Cancer 2012 ;Volum 107.(3) s. 435-441

HAUKELAND

  

 

49.  Schuster, Cornelia; Eikesdal, Hans Petter; Puntervoll, Hanne Eknes; Geisler, Jürgen; Geisler, Stephanie; Heinrich, Daniel; Molven, Anders; Lønning, Per Eystein; Akslen, Lars A.; Straume, Oddbjørn.

Clinical efficacy and safety of bevacizumab monotherapy in patients with metastatic melanoma: predictive importance of induced early hypertension. PLoS ONE 2012 ;Volum 7.(6) s. -

AHUS HAUKELAND UiB UiO

  

 

50.  Sigurdardottir, Katrin Rut; Haugen, Dagny Faksvåg; Bausewein, Claudia; Higgins, Irene J.; Harding, Richard; Rosland, Jan Henrik; Kaasa, Stein.

A pan-European survey of research in end-of-life cancer care. Supportive Care in Cancer 2012 ;Volum 20.(1) s. 39-48

HAUKELAND HVprivate NTNU STO UiB

  

 

51.  Skeie, Bente; Enger, Per Øyvind; Brøgger, Jan C; Ganz, Jeremy Christopher; Thorsen, Frits Alan; Heggdal, Jan Ingemann; Pedersen, Paal-Henning.

Gamma knife surgery versus reoperation for recurrent glioblastoma multiforme. World Neurosurgery 2012 ;Volum 78.(6) s. 658-669

HAUKELAND UiB

  

 

52.  Skotheim, Rolf Inge; Meza-Zepeda, Leonardo Andrés; Hovig, Eivind; Lønning, Per Eystein; Lothe, Ragnhild A; Myklebost, Ola.

Genomsekvensering for persontilpasset kreftbehandling. Tidsskrift for Den norske legeforening 2012 ;Volum 132. s. 2406-2408

HAUKELAND OUS

  

 

53.  Sorbye, Halfdan.

Palliative chemotherapy in elderly patients with metastatic colorectal cancer: Do we know how it should be used?. Acta Oncologica 2012 ;Volum 51.(7) s. 819-821

HAUKELAND

  

 

54.  Sorbye, Halfdan; Mauer, Murielle; Gruenberger, Thomas; Glimelius, Bengt; Poston, Graeme J.; Schlag, Peter M.; Rougier, Philippe; Bechstein, Wolf O.; Primrose, John N.; Walpole, Euan T.; Finch-Jones, Meg; Jaeck, Daniel; Mirza, Darius; Parks, Rowan W.; Collette, Laurence; Van Cutsem, Eric; Scheithauer, Werner; Lutz, Manfred P.; Nordlinger, Bernard.

Predictive Factors for the Benefit of Perioperative FOLFOX for Resectable Liver Metastasis in Colorectal Cancer Patients (EORTC Intergroup Trial 40983). Annals of Surgery 2012 ;Volum 255.(3) s. 534-539

HAUKELAND

  

 

55.  Storaas, Eivind; Holmaas, Gunhild; Gravdal, Karsten; Børretzen, Astrid; Eikesdal, Hans Petter.

Lethal pneumonitis after docetaxel chemotherapy: Case report and review of the literature. Acta Oncologica 2012

HAUKELAND

  

 

56.  Straume, Anne Hege; Knappskog, Stian; Lønning, Per Eystein.

Effect of CYP19 rs6493497 and rs7176005 haplotype status on in vivo aromatase transcription, plasma and tissue estrogen levels in postmenopausal women. Journal of Steroid Biochemistry and Molecular Biology 2012 ;Volum 128.(1-2) s. 69-75

HAUKELAND UiB

  

 

57.  Straume, Anne Hege; Løvås, Kristian; Miletic, Hrvoje; Gravdal, Karsten; Lønning, Per Eystein; Knappskog, Stian.

Elevated levels of the steroidogenic factor 1 are associated with over-expression of CYP19 in an oestrogen-producing testicular Leydig cell tumour. European Journal of Endocrinology 2012 ;Volum 166.(5) s. 941-949

HAUKELAND UiB

  

 

58.  Tahiri, Andliena; Røe, Kathrine; de Wijn, Rik; Busch, Christian; Lønning, Per Eystein; Ree, Anne Hansen; Kristensen, Vessela N.; Geisler, Jürgen.

Tyrosine kinase activity profiling of metastatic malignant melanoma: Identification of possible therapeutic targets and markers predicting response to therapy. American Association of Cancer Research; 2012-03-31 - 2012-04-04

AHUS HAUKELAND OUS

  

 

59.  Trønnes, Håvard; Haugland, Hans Kristian; Bekassy, Albert N.; Helle, Svein Inge; Sorbye, Halfdan.

Small Cell Lung Cancer in a 14-Year-Old Girl. Journal of pediatric hematology/oncology (Print) 2012 ;Volum 34.(2) s. E86-E88

HAUKELAND

  

 

60.  Westermann, Anneke; Mella, Olav; Van der Zee, Jacoba; Jones, Ellen L.; Van der Steen-Banasik, Elzbieta; Koper, Peter; Uitterhoeve, Appolina L.J.; de Wit, Ronald; van der Velden, 61.Jacobus; Burger, Curt; Schem, Baard-Christian; Van der Wilt, Clasina L.; Dahl, Olav; Prosnitz, Leonard R.; van Tinteren, Harm.

Long-term survival data of triple modality treatment of stage IIB-III-IVA cervical cancer with the combination of radiotherapy, chemotherapy and hyperthermia - an update. International Journal of Hyperthermia 2012 ;Volum 28.(6) s. 549-553

HAUKELAND UiB

   

 

62.  Ånensen, Nina; Hjelle, Sigrun Margrethe; Van, Belle Werner; Haaland, Ingvild; Silden, Elisabeth; Bourdon, Jean-Christophe; Hovland, Randi; Tasken, Kjetil; Knappskog, Stian; Lønning, Per Eystein; Bruserud, Øystein; Gjertsen, Bjørn Tore.

Correlation analysis of p53 protein isoforms with NPM1/FLT3 mutations and therapy response in acute myeloid leukemia. Oncogene 2012 ;Volum 31.(12) s. 1533-1545

HAUKELAND NORUT UiB UiO


 

1. Oftedal, Linn Silje Wathne; Skjærven, Kaja Helvik; Coyne, Rosie Theresa; Edvardsen, Bente; Rohrlack, Thomas; Skulberg, Olav; Doskeland, Stein Ove; Herfindal, Lars. 
The apoptosis-inducing activity towards leukemia and lymphoma cells in a cyanobacterial culture collection is not associated with mouse bioassay toxicity. Journal of Industrial Microbiology & Biotechnology 2011 ;Volum 38.(4) s. 489-501
HAUKELAND NIVA UiB UiO

2. Akslen, Lars A.; Straume, Oddbjørn; Geisler, Stephanie; Sørlie, Therese; Chi, Jen-Tan Ashley; Aas, Turid; Børresen-Dale, Anne-Lise; Lønning, Per Eystein. 
Glomeruloid microvascular proliferation is associated with lack of response to chemotherapy in breast cancer. British Journal of Cancer 2011 ;Volum 105.(1) s. 9-12
HAUKELAND UiB UiO

3. Balteskard, Lise; Dahl, Olav; Guren, Marianne; Haraldsen, Mathilde; Strickert, Trond; Wanderås, Eva Hoff; Heikkilä, Ingrid Espe; Hellebust, Taran Paulsen; Frykholm, Gunilla. 
Faglige anbefalinger for behandling ved analcancer.. StrålevernRapport 2011 ;Volum 5. s. 1-34
HAUKELAND STO HN OUS

4. Berge, Elisabet Ognedal; Knappskog, Stian; Lillehaug, Johan R.; Lønning, Per Eystein. 
Alterations of the retinoblastoma gene in metastatic breast cancer. Clinical and Experimental Metastasis 2011 ;Volum 28.(3) s. 319-326
HAUKELAND UiB

5. Cao, Maria Dung; Jiang, Lu; Krishnamachary, Balaji; Doepkens, Mailin; Vesuna, Farhad; Lønning, Per Eystein; Bhjuwalla, Zaver M.; Gribbestad, Ingrid S; Glunde, Kristine. 
GDPD5 expression correlates with choline metabolite profiles in human breast cancer. FUGE workshop; 2011-09-07 - 2011-09-09
HAUKELAND NTNU

6. Chrisanthar, Ranjan; Knappskog, Stian; Løkkevik, Erik; Anker, Gun Birgitta; Østenstad, Bjørn; Lundgren, Steinar; Risberg, Terje; Mjaaland, Ingvil; Skjønsberg, Gudbrand; Aas, Turid; Schlichting, Ellen; Fjøsne, Hans Erikssønn; Nysted, Arne; Lillehaug, Johan R.; Lønning, Per Eystein. 
Predictive and Prognostic Impact of TP53 Mutations and MDM2 Promoter Genotype in Primary Breast Cancer Patients Treated with Epirubicin or Paclitaxel. PLoS ONE 2011 ;Volum 6.(4) s. -
HAUKELAND NTNU OUS STO SUS UiB UiT UNN

7. Dowsett, Mitch; Lønning, Per Eystein. 
Special Issue 10th International Aromatase Conference Proceedings, September 2010 Preface. Steroids 2011 ;Volum 76.(8) s. 729-729
HAUKELAND UiB

8. Eide, Marianne Brodtkorb; Lauritzsen, Grete Fossum; Kvalheim, Gunnar; Kolstad, Arne; Fagerli, Unn-Merete; Maisenhölder, Martin; Østenstad, Bjørn; Fluge, Øystein; Delabie, Jan; Aarset, Harald; Liestøl, Knut; Holte, Harald. 
High dose chemotherapy with autologous stem cell support for patients with histologically transformed B-cell non-Hodgkin lymphomas. A Norwegian multi centre phase II study. British Journal of Haematology 2011 ;Volum 152.(5) s. 600-610
HAUKELAND OUS STO UiO UNN

9. Eikesdal, Hans Petter; Kalluri, Raghu. 
The multifaceted role of cancer associated fibroblasts in tumor progression. I: Tumor-associated fibroblasts and their matrix. Springer 2011 ISBN 9789400706583. s. 361-380
HAUKELAND

10. Fjøsne, Hans Erikssønn; Søreide, Jon Arne; Kåresen, Rolf; Lønning, Per Eystein; Jacobsen, Anne-Birgitte; Lundgren, Steinar. 
Hospital volume and prognosis among Norwegian breast cancer patients enrolled in adjuvant trials. Acta Oncologica 2011 ;Volum 50.(7) s. 1068-1074
HAUKELAND NTNU OUS STO SUS UiB UiO

11. Fluge, Øystein; Bruland, Ove; Risa, Kristin; Storstein, Anette; Kristoffersen, Einar Klæboe; Sapkota, Dipak; Næss, Halvor; Dahl, Olav; Nyland, Harald Inge; Mella, Olav. 
Benefit from B-lymphocyte depletion using the anti-CD20 antibody rituximab in chronic fatigue syndrome. A double-blind and placebo-controlled study. PLoS ONE 2011 ;Volum 6.(10) s. -
HAUKELAND UiB

12. Flågeng, Marianne Hauglid; Knappskog, Stian; Lønning, Per Eystein; Mellgren, Gunnar. 
The nuclear receptor coactivator PELP1/MNAR is positively correlated with estrogen levels in breast cancer patients. Nuclear receptors - from molecular mechanisms to health and disease; 2011-09-16 - 2011-09-20
HAUKELAND UiB

13. Fors, Egil Andreas; Bertheussen, Gro Falkener; Thune, Inger; Juvet, Lene Kristine; Elvsaas, Ida-Kristin Ørjasæter; Oldervoll, Line Merethe; Anker, Gun Birgitta; Falkmer, Ursula; Lundgren, Steinar; Leivseth, Gunnar. 
Psychosocial interventions as part of breast cancer rehabilitation programs? Results from a systematic review. Psycho-Oncology 2011 ;Volum 20.(9) s. 909-918
HAUKELAND NOKC NTNU OUS STO

14. Glimelius, Bengt; Garmo, Hans; Berglund, Åke; Fredriksson, Lennart A.; Berglund, Mattias; Kohnke, Hugo; Byström, Pär; Sørbye, Halfdan; Wadelius, Mia. 
Prediction of irinotecan and 5-fluorouracil toxicity and response in patients with advanced colorectal cancer. The Pharmacogenomics Journal 2011 ;Volum 11.(1) s. 61-71
HAUKELAND

15. Herfindal, Lars; Myhren, Lene Elisabeth; Kleppe, Rune; Krakstad, Camilla; Selheim, Frode; Jokela, Jouni; Sivonen, Kaarina; Doskeland, Stein Ove. 
Nostocyclopeptide-M1: A potent, nontoxic inhibitor of the hepatocyte drug transporters OATP1B3 and 1B1. Molecular Pharmaceutics 2011 ;Volum 8.(2) s. 360-367
HAUKELAND UiB

16. Hesstvedt, Liv; Wilhelmsen, Marianne; Mengshoel, Anne T; Dyrhol-Riise, Anne Ma. 
Two Norwegian patients with melioidosis presenting with bacteraemia and splenic and prostatic abscesses. Journal of Travel Medicine 2011 ;Volum 18.(6) s. 418-421
HAUKELAND OUS

17. Hjermstad, Marianne Jensen; Fayers, Peter; Haugen, Dagny R Faksvåg; Caraceni, Augusto; Hanks, Geoffrey; Loge, Jon Håvard; Fainsinger, Robin; Aass, Nina; Kaasa, Stein. 
Studies Comparing Numerical Rating Scales, Verbal Rating Scales, and Visual Analogue Scales for Assessment of Pain Intensity in Adults: A Systematic Literature Review. Journal of Pain Symptom and Management 2011 ;Volum 41.(6) s. 1073-1093
HAUKELAND NTNU OUS STO UiO

18. Holte, Harald; Bogsrud, Trond; Leppa, S.; Laukka, M.; Bjørkholm, Mikaela; Jacobsson, H.; Jyrkkio, S.; Seppanen, M.; Jerkeman, Mats; Brun, E.; Fluge, Øystein; Pedersen, Lone Møller. 
(18)FDG PET/CT AFTER INTENSIFIED CHEMO-IMMUNOTHERAPY IN DIFFUSE LARGE B-CELL LYMPHOMA (DLBCL), AGED 18-65 YEARS WITH AAIPI 2-3. POSITIVE OR INDETERMINATE LESIONS HAVE A LOW POSITIVE PREDICTIVE VALUE. A NORDIC PHASE II SUBSTUDY. Annals of Oncology 2011 ;Volum 22. s. 159-159
HAUKELAND OUS UiO

19. Hysing, Liv Bolstad. 
Exploring and exploiting the potential of pelvic IMRT to spare the bowel. : University of Bergen 2011 (ISBN 978-82-308-1864-0) 
HAUKELAND UiB

20. Hysing, Liv Bolstad; Söhn, Matthias; Muren, Ludvig Paul; Alber, Markus. 
A coverage probability based method to estimate patient-specific small bowel planning volumes for use in radiotherapy. Radiotherapy and Oncology 2011 ;Volum 100.(3) s. 407-411
HAUKELAND

21. Jaatun, Ellen A. Andreassen; Haugen, Dagny Faksvåg; Seland, Gry; Sørby, Inger Dybdahl; Faxvaag, Arild; Hjermstad, Marianne Jensen; Kaasa, Stein. 
Formative usability evaluation of a computerized pain body map. The 5th International Symposium on Human Factors Engineering in Health Informatics; 2011-08-26 - 2011-08-27
HAUKELAND NTNU STO

22. Jebsen, Nina; Bruland, Øyvind; Eriksson, Mikael; Engellau, Jacob; Turesson, Ingela; Folin, Annika; Trovik, Clement S; Hall, Kirsten Sundby. 
Five-year results from a Scandinavian sarcoma group study (SSG XIII) of adjuvant chemotherapy combined with accelerated radiotherapy in high-risk soft tissue sarcoma of extremities and trunk wall. International Journal of Radiation Oncology, Biology, Physics 2011 ;Volum 81.(5) s. 1359-1366
HAUKELAND OUS UiB UiO

23. Jenum, Anne Karen; Mørkrid, Kjersti; Sletner, Line; Vangen, Siri; Torper, Johan; Nakstad, Britt; Voldner, Nanna; Rognerud-Jensen, Odd H.; Stølevik, Sveinung Berntsen; Mosdøl, Annhild; Skrivarhaug, Torild; Vårdal, Mari H; Holme, Ingar Morten K; Yajnik, Chittaranjan S; Birkeland, Kåre I.. 
Impact of ethnicity on gestational diabetes identified with the WHO and the modified International Association of Diabetes and Pregnancy Study Groups criteria: a population-based cohort study. European Journal of Endocrinology 2011 s. -
AHUS HAUKELAND HIAK HiO OUS UIA UiO

24. Kaasa, Stein; Haugen, Dagny R Faksvåg. 
Cancer pain research: Time to reset the strategy and the agenda. Palliative Medicine : A Multiprofessional Journal 2011 ;Volum 25.(5) s. 392-393
HAUKELAND NTNU STO

25. Knappskog, Stian; Bjørnslett, Merete Pauline; Myklebust, Line Merethe; Huijts, Petra E.A.; Vreeswijk, Maaike P.; Edvardsen, Hege; Guo, Yongli; Zhang, Xuemei; Yang, Ming; Ylisaukko-oja, Sanna K.; Alhopuro, Pia; Arola, Johanna; Tollenaar, Rob A.E.M.; van Asperen, Christi J; Seynaeve, Caroline; Staalesen, Vidar; Chrisanthar, Ranjan; Løkkevik, Erik; Salvesen, Helga Birgitte; Evans, D. Gareth; Newman, William G.; Lin, Dongxin; Aaltonen, Lauri; Børresen-Dale, Anne-Lise; Tell, Grethe S; Stoltenberg, Camilla; Romundstad, Pål Richard; Hveem, Kristian; Lillehaug, Johan R.; Vatten, Lars Johan; Devilee, Peter; Dørum, Anne; Lønning, Per Eystein. 
The MDM2 Promoter SNP285C/309G Haplotype Diminishes Sp1 Transcription Factor Binding and Reduces Risk for Breast and Ovarian Cancer in Caucasians. Cancer Cell 2011 ;Volum 19.(2) s. 273-282
FHI HAUKELAND NTNU OUS UiB UiO

26. Knappskog, Stian; Lønning, Per Eystein. 
MDM2 promoter SNP285 and SNP309; phylogeny and impact on cancer risk. OncoTarget 2011 ;Volum 2.(3) s. 251-258
HAUKELAND UiB

27. Knappskog, Stian; Myklebust, Line Merethe; Busch, Christian; Aloysius, Thomas Aquinas; Varhaug, Jan Erik; Lønning, Per Eystein; Lillehaug, Johan R.; Pendino, Frederic. 
RINF (CXXC5) is overexpressed in solid tumors and is an unfavorable prognostic factor in breast cancer(dagger). Annals of Oncology 2011 ;Volum 22.(10) s. 2208-2215
HAUKELAND UiB

28. Larssen, Lene; Medhus, Asle Wilhelm; Hjermstad, Marianne Jensen; Kørner, Hartwig; Glomsaker, Tom; Søberg, Taran; Gleditsch, Dagfinn; Hovde, Øistein; Nesbakken, Arild; Tholfsen, Jan Karl; Skreden, Knut; Hauge, Truls. 
Patient-reported outcomes in palliative gastrointestinal stenting: a Norwegian multicenter study. Surgical Endoscopy 2011 ;Volum 25.(10) s. 3162-3169
HAUKELAND HNT NTNU OSTFSYK OUS SI SUS UiB UiO VV

29. Lehne, Gustav; Angelsen, Anders; Langberg, Carl W.; Dahl, Olav; Bremnes, Roy M.; Tandstad, Torgrim; Wahlqvist, Rolf; Haugnes, Hege Sagstuen. 
Nasjonalt handlingsprogram med retningslinjer for diagnostikk, behandling og oppfølging av testikkelkreft.. : Helsedirektoratet 2011 (ISBN 978-82-8081-227-8) 109 s. 
HAUKELAND STO UiT OUS NTNU

30. Lybak, Stein; Liavaag, Per Gunnar; Monge, Odd R; Olofsson, Jan. 
Surgery and postoperative radiotherapy a valid treatment for advanced oropharyngeal carcinoma. European Archives of Oto-Rhino-Laryngology 2011 ;Volum 268.(3) s. 449-456
HAUKELAND

31. Lønning, Per Eystein. 
The potency and clinical efficacy of aromatase inhibitors across the breast cancer continuum. Annals of Oncology 2011 ;Volum 22.(3) s. 503-514
HAUKELAND UiB

32. Lønning, Per Eystein; Haynes, Ben P.; Straume, Anne Hege; Dunbier, Anita; Helle, Hildegunn; Knappskog, Stian; Dowsett, Mitch. 
Exploring breast cancer estrogen disposition: The basis for endocrine manipulation. Clinical Cancer Research 2011 ;Volum 17.(15) s. 4948-4958
HAUKELAND UiB

33. Lønning, Per Eystein; Haynes, Ben P.; Straume, Anne Hege; Dunbier, Anita; Helle, Hildegunn; Knappskog, Stian; Dowsett, Mitch. 
Recent data on intratumor estrogens in breast cancer. Steroids 2011 ;Volum 76.(8) s. 786-791
HAUKELAND UiB

34. Mohn, Silje; Wasbø, Ellen. 
Simulation of respiratory motion during IMRT dose delivery. Acta Oncologica 2011 ;Volum 50.(6) s. 935-943
HAUKELAND NTNU

35. Myklebust, Mette Pernille; Bruland, Ove; Fluge, Øystein; Skarstein, Arne; Balteskard, Lise; Dahl, Olav. 
MicroRNA-15b is induced with E2F-controlled genes in HPV-related cancer. British Journal of Cancer 2011 ;Volum 105.(11) s. 1719-1725
HAUKELAND UiB UNN

36. Oldervoll, Line Merethe; Loge, Jon Håvard; Lydersen, Stian; Paltiel, Hanne; Asp, May-Britt; Nygaard, Unni Vidvei; Oredalen, Elisabeth; Frantzen, Tone-Lise; Lesteberg, Ingvild; Amundsen, Lise; Hjermstad, Marianne Jensen; Haugen, Dagny Faksvåg; Paulsen, Ørnulf; Kaasa, Stein. 
Physical Exercise for Cancer Patients with Advanced Disease: A Randomized Controlled Trial. The Oncologist 2011 ;Volum 16.(11) s. 1649-1657
HAUKELAND HVprivate LDS NTNU OUS STHF STO

37. Olofsson, Sven-Erik; Tandstad, Torgrim; Jerkeman, Mats; Dahl, Olav; Ståhl, Olof; Klepp, Olbjørn; Bremnes, Roy M.; Cohn-Cedermark, Gabriella; Langberg, Carl W.; Laurell, Anna; Solberg, Arne; Stierner, Ulrika; Wahlqvist, Rolf; Wijkström, Hans; Anderson, Harald; Cavallin-Ståhl, Eva. 
Population-based study of treatment guided by tumor marker decline in patients with metastatic nonseminomatous germ cell tumor: a report from the Swedish-Norwegian testicular cancer group. Journal of Clinical Oncology 2011 ;Volum 29.(15) s. 2032-2039
HAUKELAND OUS STO UiB UiT UNN

38. Rades, Dirk; Setter, Cornelia; Dahl, Olav; Schild, Steven E.; Noack, Frank. 
Prognostic impact of erythropoietin expression and erythropoietin receptor expression on locoregional control and survival of patients irradiated for stage II/III non-small-cell lung cancer. International Journal of Radiation Oncology, Biology, Physics 2011 ;Volum 80.(2) s. 499-505
HAUKELAND UiB

39. Ries, Anke; Trottenberg, Peter; Elsner, Frank; Stiel, Stephanie; Haugen, Dagny Faksvåg; Kaasa, Stein; Radbruch, Lukas. 
A systematic review on the role of fish oil for the treatment of cachexia in advanced cancer: An EPCRC cachexia guidelines project. Palliative Medicine : A Multiprofessional Journal 2011 s. -
HAUKELAND NTNU

40. Skeie, Bente; Skeie, Geir Olve; Enger, Per Øyvind; Ganz, Jeremy Christopher; Heggdal, Jan Ingemann; Ystevik, Birgit; Hatteland, Signe; Parr, Elisabeth; Pedersen, Paal-Henning. 
Gamma Knife Surgery in Brain Melanomas: Absence of Extracranial Metastases and Tumor Volume Strongest Indicators of Prolonged Survival. World Neurosurgery 2011 ;Volum 75.(5-6) s. 684-691
HAUKELAND UiB

41. Smeland, Sigbjørn; Bruland, Øyvind; Hjorth, Lars; Brosjö, Otte; Bjerkehagen, Bodil; Österlundh, Gustaf; Jakobson, Åke; Hall, Kirsten Sundby; Monge, Odd R; Björk, Olle; Alvegaard, Thor A.. 
Results of the Scandinavian Sarcoma Group XIV protocol for classical osteosarcoma 63 patients with a minimum follow-up of 4 years. Acta Orthopaedica 2011 ;Volum 82.(2) s. 211-216
HAUKELAND OUS UiO

42. Strand, Trond-Eirik; Brunsvig, Paal Fr.; Johannessen, Dag Clement; Sundstrøm, Stein Harald; Wang, Mari; Hornslien, Kjersti; Bremnes, Roy M.; Stensvold, Andreas; Garpestad, Oddveig Karin; Norstein, Jarle. 
Potentially curative radiotherapy for non–small-cell lung cancer in Norway: A population-based study of survival. International Journal of Radiation Oncology, Biology, Physics 2011 ;Volum 80.(1) s. 133-141
HAUKELAND KREFTREG OUS STO SUS UiT

43. Tandstad, Torgrim; Smaaland, Rune; Solberg, Arne; Bremnes, Roy M.; Langberg, Carl W.; Laurell, Anna; Stierner, Ulrika; Ståhl, Olof; Cavallin-Ståhl, Eva; Klepp, Olbjørn; Dahl, Olav; Cohn-Cedermark, Gabriella. 
Management of Seminomatous Testicular Cancer: A Binational Prospective Population-Based Study From the Swedish Norwegian Testicular Cancer Study Group. Journal of Clinical Oncology 2011 ;Volum 29.(6) s. 719-725
HAUKELAND HSM OUS STO SUS UiB UiT UNN

44. Thornqvist, Sara; Bentzen, Lise; Petersen, Jorgen BB; Hysing, Liv Bolstad; Muren, Ludvig Paul. 
Plan robustness of simultaneous integrated boost radiotherapy of prostate and lymph nodes for different image-guidance and delivery techniques. Acta Oncologica 2011 ;Volum 50.(6) s. 926-934
HAUKELAND UiB

45. Welin, Staffan; Sørbye, Halfdan; Sebjørnsen, Sigrunn; Knappskog, Stian; Busch, Christian; Öberg, Kjell. 
Clinical effect of Temozolomide-based chemotherapy in poorly differentiated endocrine carcinoma after progression on first-line chemotherapy. Cancer 2011 ;Volum 117.(20) s. 4617-4622
HAUKELAND UiB

46. Yri, Olav Erich; Torfoss, Dag; Hungnes, Olav; Tierens, Anne; Waalen, Kristian; Nordøy, Tone; Dudman, Susanne Gjeruldsen; Kilander, Anette; Wader, Karin Fahl; Østenstad, Bjørn; Ekanger, Roald; Meyer, Peter Albert; Kolstad, Arne. 
Rituximab blocks protective serologic response to influenza A (H1N1) 2009 vaccination in lymphoma patients during or within 6 months after treatment. Blood 2011 ;Volum 118.(26) s. 6769-6771
FHI HAUKELAND OUS STO SUS UNN

47. Ånensen, Nina; Hjelle, Sigrun Margrethe; Van Belle, Werner; Haaland, Ingvild; Silden, Elisabeth; Bourdon, Jean-Christophe; Hovland, Randi; Tasken, Kjetil; Knappskog, Stian; Lønning, Per Eystein; Bruserud, Øystein; Gjertsen, Bjørn Tore. 
Correlation analysis of p53 protein isoforms with NPM1/FLT3 mutations and therapy response in acute myeloid leukemia. Oncogene 2011 
HAUKELAND NORUT UiB UiO 


 

Berge, Elisabet Ognedal; Knappskog, Stian; Geisler, Stephanie; Staalesen, Vidar; Pacal, Marec; Børresen-Dale, Anne-Lise; Puntervoll, Pål; Lillehaug, Johan R.; Lønning, Per Eystein. 
Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancers. Molecular Cancer 2010; Volum 9. s. -
UiB UiO UNI 

Berge, Elisabet Ognedal; Staalesen, Vidar; Straume, Anne Hege; Lillehaug, Johan R.; Lønning, Per Eystein. 
Chk2 splice variants express a dominant-negative effect on the wild-type Chk2 kinase activity. Biochimica et Biophysica Acta. Molecular Cell Research 2010; Volum 1803.(3) s. 386-395
UiB   

Bruheim, K; Guren, MG; Skovlund, E; Hjermstad, Marianne Jensen; Dahl, O; Frykholm, Gunilla; Carlsen, Erik; Tveit, KM. 
Late side effects and quality of life after radiotherapy for rectal cancer. International Journal of Radiation Oncology, Biology, Physics 2010; Volum 76.(4) s. 1005-1011
NTNU UiO UiB   

Brydøy, Marianne; Fosså, Sophie D; Klepp, Olbjørn; Bremnes, Roy M.; Wist, Erik; Wentzel-Larsen, Tore; Dahl, Olav. 
Paternity and Testicular Function Among Testicular Cancer Survivors Treated With Two to Four Cycles of Cisplatin-Based Chemotherapy. European Urology 2010; Volum 58.(1) s. 134-140
UiB UiO UiT 

Busch, Christian; Geisler, Jürgen; Knappskog, Stian; Lillehaug, Johan R.; Lønning, Per Eystein. 
Alterations in the p53 Pathway and p16INK4a Expression Predict Overall Survival in Metastatic Melanoma Patients Treated with Dacarbazine. Journal of Investigative Dermatology 2010; Volum 130.(10) s. 2514-2516
UiB

  
Busch, Christian; Geisler, Jürgen; Lillehaug, Johan R.; Lønning, Per Eystein. 
MGMT expression levels predict disease stabilisation, progression-free and overall survival in patients with advanced melanomas treated with DTIC. European Journal of Cancer 2010; Volum 46.(11) s. 2127-2133
UiB   

Cao, Maria Dung; Sitter, Beathe; Bathen, Tone Frost; Bofin, Anna M.; Lønning, Per Eystein; Lundgren, Steinar; Gribbestad, Ingrid S. 
Predicting long-term breast cancer survival in patients receiving neoadjuvant chemotherapy by MR metabolic profiling. MI Lab day; 2010-04-29
UiB NTNU   

Cao, Maria Dung; Sitter, Beathe; Bathen, Tone Frost; Bofin, Anna M.; Lønning, Per Eystein; Lundgren, Steinar; Gribbestad, Ingrid S. 
Predicting long-term survival for breast cancer patients by HR MAS metabolic profiling during neoadjuvant chemotherapy. ISMRM 2010; 2010-05-01 - 2010-05-07
UiB NTNU   

Dahl, Christian Falk; Haugnes, Hege Sagstuen; Bremnes, Roy M.; Dahl, Olav; Fosså, Sophie Dorothea; Klepp, Olbjørn; Wist, Erik; Dahl, Alv A. 
A controlled study of risk factors for disease and current problems in long-term testicular cancer survivors.. Journal of cancer survivorship 2010; Volum 4.(3) s. 256-265
NTNU UiB UiO UiT 

Dejeux, Emelyne; Rønneberg, Jo Anders; Solvang, Hiroko Kato; Bukholm, Ida R. K.; Geisler, Stephanie; Aas, Turid; Gut, Ivo G.; Børresen-Dale, Anne-Lise; Lønning, Per Eystein; Kristensen, Vessela Nedelcheva; Tost, Jörg. 
DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response. Molecular Cancer 2010; Volum 9. s. -
UiB UiO 

Flågeng, Marianne Hauglid; Knappskog, Stian; Larionov, Alexey; Geisler, Jurgen; Dixon, Mike; Miller, William R.; Lønning, Per Eystein; Mellgren, Gunnar. 
Epidermal growth factor receptors (ErbB/HER) and the ligand Neuregulin 1 (NRG1) increase in breast tumors during short time treatment with aromatase inhibitors. 33RD annual San Antonio breast cancer symposium; 2010-12-08 - 2010-12-12
UiB UiO 

Geisler, Jurgen; Lønning, Per Eystein. 
Impact of aromatase inhibitors on bone health in breast cancer patients.. Journal of Steroid Biochemistry and Molecular Biology 2010; Volum 118.(4-5) s. 294-299
UiB UiO   

Geisler, Jurgen; Suzuki, Takashi; Helle, Hildegunn; Miki, Yasuhiro; Nagasaki, Shuji; Duong, Nhat Kim; Ekse, Dagfinn; Aas, Turid; Evans, Dean B.; Lønning, Per Eystein; Sasano, Hironobu. 
Breast cancer aromatase expression evaluated by the novel antibody 677: Correlations to intra-tumor estrogen levels and hormone receptor status.. Journal of Steroid Biochemistry and Molecular Biology 2010; Volum 118.(4-5) s. 237-241
UiB UiO   

Haugnes, Hege Sagstuen; Wethal, Torgeir; Aass, Nina Kathrine; Dahl, Olav; Klepp, Olbjørn; Langberg, Carl W.; Wilsgaard, Tom; Bremnes, Roy M.; Fosså, Sophie Dorothea. 
Cardiovascular risk factors and morbidity in long-term survivors of testicular cancer: a 20-year follow-up study. Journal of Clinical Oncology 2010; Volum 28.(30) s. 4649-4657
NTNU UiB UiO UiT 

Haynes, Ben P.; Straume, Anne Hege; Geisler, Jurgen; A'Hern, Roger; Helle, Hildegunn; Smith, Ian E; Lønning, Per Eystein; Dowsett, Mitch. 
Intratumoral estrogen disposition in breast cancer. Clinical Cancer Research 2010; Volum 16.(6) s. 1790-1801
UiB UiO   

Janson, ET; Sørbye, Halfdan; Welin, S; Federspiel, B; Grønbæk, H; Hellman, P; Mathisen, Ø; Mortensen, J; Sundin, S; Thiis-Evensen, E; Välimäki, M; Öberg, Kjell; Knigge, U. 
Nordic Guidelines 2010 for Diagnosis and Treatment of Gastroenteropancreatic Neuroendicrine Tumours.. Acta Oncologica 2010; Volum 49.(6) s. 740-756
UiB   

Jebsen, Nina; Bruland, Øyvind; Eriksson, Mikael; Engellau, Jacob; Turesson, I; Folin, Annika; Trovik, Clement S; Hall, Kirsten Sundby. 
Five-Year Results From a Scandinavian Sarcoma Group Study (SSG XIII) of Adjuvant Chemotherapy Combined With Accelerated Radiotherapy in High-Risk Soft Tissue Sarcoma of Extremities and Trunk Wall. International Journal of Radiation Oncology, Biology, Physics 2010 s. -
UiB UiO

Jönsson, Göran; Busch, Christian; Knappskog, Stian; Miletic, Hrvoje; Ringnér, Markus; Lillehaug, Johan R.; Borg, Åke; Lønning, Per Eystein. 
Gene Expression Profiling-Based Identification of Molecular Subtypes in Stage IV Melanomas with Different Clinical Outcome. Clinical Cancer Research 2010; Volum 16.(13) s. 3356-3367
UiB 

Kvåle, Rune; Møller, Bjørn; Angelsen, Anders; Dahl, Olav; Fosså, Sophie Dorothea; Halvorsen, Ole Johan; Hoem, L; Solberg, Anette; Wahlqvist, Rolf; Bray, Freddie Ian. 
Regional trends in prostate cancer incidence, treatment with curative intent and mortality in Norway 1980-2007. Cancer Detection and Prevention 2010; Volum 34.(4) s. 359-367
UiB UiO   

Ladstein RG, Bachmann IM, Straume Oddbjørn, Akslen LA. KI-67 expression is superior to mitotic count and novel proliferation markers PHH3, MCM4 and mitosin as a prognostic factor in thick cutaneous melanoma. BMC Cancer 2010, Volum 10, s 140.

Lønning, Per Eystein. 
Are current development programs realising the full potential of new agents?. Breast Cancer Research 2010; Volum 12. Suppl. 4 s. s23-s26
HBE UiB   

Lønning, Per Eystein. 
Evolution of endocrine adjuvant therapy for early breast cancer. Expert Opinion on Investigational Drugs 2010; Volum 19. Suppl. S1 s. S19-S30
UiB   

Lønning, Per Eystein. 
Molecular basis for therapy resistance. Molecular Oncology 2010; Volum 4.(3) s. 284-300
UiB   

Lønning, Per Eystein. 
The potency and clinical efficacy of aromatase inhibitors across the breast cancer continuum.. Annals of Oncology 2010 
HBE UiB   

Lønning, Per Eystein; Geisler, Jürgen. 
Evaluation of plasma and tissue estrogen suppression with third-generation aromatase inhibitors: Of relevance to clinical understanding?. Journal of Steroid Biochemistry and Molecular Biology 2010; Volum 118.(4-5) s. 288-293UiB UiO  

Marienhagen K, Helland A, Nordberg Terje, Guren MG, Hofsli E. [How do Norwegian oncologists perceive their working conditions? [Article in Norwegian]. Tidsskr Nor Laegeforen.2010; Volum 130 (5). s 487-9.

Mouridsen, Henning T; Lønning, Per Eystein; Beckmann, Matthias W; Blackwell, Karen; Doughty, Julie; Gligorov, Joseph; Llombart-Cussac, Antonio; Robidoux, Andre; Thurlimann, Beat; Gnant, Michael. 
Use of aromatase inhibitors and bisphosphonates as an anticancer therapy in postmenopausal breast cancer. Expert Review of Anticancer Therapy 2010; Volum 10.(11) s. 1825-1836
UiB 

Rades, Dirk; Setter, Cornelia; Dunst, Jürgen; Dahl, Olav; Schild, Steven E.; Noack, Frank. 
Prognostic Impact of VEGF and VEGF Receptor 1 (FLT1) Expression in Patients Irradiated for Stage II/III Non-Small Cell Lung Cancer (NSCLC). Strahlentherapie und Onkologie (Print) 2010; Volum 186.(6) s. 307-314
UiB   

Sund M, Nyberg P, Eikesdal HP. Endogenous matrix-derived inhibitors of angiogenesis. Pharmaceuticals 2010; 3(10): 3021-3039.   

Sæther HK, Lagesen B, Trægde Martinsen AC, Holsen EP, Øvrebø Kirsti Mari. Dose levels from thoracic and pelvic examinations in two pediatric radiological departments in Norway – a comparison study of dose-area product and radiographic technique. Acta Radiol. 2010 Dec;51(10):1137-42. 

Tandstad, Torgrim; Cohn-Cedermark, Gabriella; Dahl, Olav; Stierner, Ulrika; Cavallin-Ståhl, Eva; Bremnes, Roy M.; Klepp, Olbjørn. 
Long-term follow-up after risk-adapted treatment in clinical stage 1 (CS1) nonseminomatous germ-cell testicular cancer (NSGCT) implementing adjuvant CVB chemotherapy. A SWENOTECA study. Annals of Oncology 2010; Volum 21. s. 1858-1863
UiB UiT 

Thoresen, G. Hege; Dahl, Olav; Christoffersen, Thoralf. 
L2 Legemidler i behandlingen av kreftsykdommer. I: Norsk legemiddelhåndbok for helsepersonell 2010. Oslo: Foreningen for utgivelse av norsk legemiddelhåndbok 2010 ISBN 9788290732108. s. 775-820
UiB UiO 

Torsvik, Anja; Røsland, Gro Vatne; Svendsen, Agnete; Molven, Anders; Immervoll, Heike; McCormack, Emmet Martin; Lønning, Per Eystein; Primon, Monica; Sobala, Ewa; Tonn, Jörg Christian; Goldbrunner, Roland; Schichor, Christian; Mysliwietz, Josef; Lah, Tamara; Motaln, Helena; Knappskog, Stian; Bjerkvig, Rolf. 
Spontaneous Malignant Transformation of Human Mesenchymal Stem Cells Reflects Cross-Contamination: Putting the Research Field on Track - Letter. Cancer Research 2010; Volum 70.(15) s. 6393-6396
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Last updated 1/29/2018