GEMRIC - The Global ECT-MRI Research Collaboration

Brain changes induced by electroconvulsive therapy (ECT) – understanding treatment mechanisms and predictors of clinical response.

Published 01.03.2019 / Last updated 19.05.2022

The Global ECT-MRI Research Collaboration was founded at a collaborative meeting in Bergen in June 2015, and is coordinated by Leif Oltedal. The principal idea behind this initiative is that collaboration and mega-analyses of combined study data will lead to new discoveries. In the first phase, GEMRIC will include up to 550 subjects including patients (clinical and neuroimaging data before and after ECT) and controls (healthy or patients with depression that receive other treatments). However, with our latest study “The GEMRIC study for determining the mechanisms of action of electroconvulsive therapy”, the collaboration will be extended and we aim at increasing the sample size to 2000 subjects.

gemric.org

Mohn Medical Imaging Visualization Centre

Publications

Akihiro Takamiya, Annemiek Dols, Louise Emsell, Christopher Abbott, Antoine Yrondi, Carles Soriano Mas, Martin Balslev Jorgensen, Pia Nordanskog, Didi Rhebergen, Eric van Exel, Mardien L. Oudega, Filip Bouckaert , Mathieu Vandenbulcke, Pascal Sienaer, Patrice Péran, Marta Cano, Narcis Cardoner, Anders Jorgensen, Olaf B. Paulson, Paul Hamilton, Robin Kampe, Willem Bruin, Hauke Bartsch, Olga Therese Ousdal, Ute Kessler, Guido van Wingen, Leif Oltedal, and Taishiro Kishimoto. (2021) Neural Substrates of Psychotic Depression: Findings From the Global ECT-MRI Research Collaboration. Schizophrenia Bulletin https://doi.org/10.1093/schbul/sbab122 Download PDF

Opel, N., Narr, K., Abbott, C., Argyelan, M., …, Ousdal, O., Haavik, J., Hammar, Å., Oedegaard, K., Kessler, U., Bartsch, H., Dale, A., Baune, B., Dannlowski, Oltedal, L., & Redlich, R.. (2021). Elevated body weight modulates subcortical volume change and associated clinical response following electroconvulsive therapy. Journal of psychiatry & neuroscience, 46(6), PE418–E426. doi:10.1503/jpn.200176 Download PDF

P. C. Mulders, A. Llera, C. F. Beckmann, M. Vandenbulcke, M. Stek, P. Sienaert, R. Redlich, G. Petrides, M. L. Oudega, L. Oltedal, and others, “Structural changes induced by electroconvulsive therapy are associated with clinical outcome,” Brain Stimulation, 2020. doi:10.1016/j.brs.2020.02.020 Download PDF

2019

O. T. Ousdal, M. Argyelan, K. L. Narr, C. Abbott, B. Wade, M. Vandenbulcke, M. Urretavizcaya, I. Tendolkar, A. Takamiya, M. L. Stek, and others, “Brain changes induced by Electroconvulsive Therapy are broadly distributed,” Biological Psychiatry, 2019. https://doi.org/10.1016/j.biopsych.2019.07.010 Download PDF

Leif Oltedal, Katherine L. Narr, Christopher Abbott, Amit Anand, Miklos Argyelan, Hauke Bartsch, Udo Dannlowski, Annemieke Dols, Philip van Eijndhoven, Louise Emsell, Vera Jane Erchinger, Randall Espinoza, Tim Hahn, Lars G. Hanson, Gerhard Hellemann, Martin Balslev Jorgensen, Ute Kessler, Mardien L. Oudega, Olaf B. Paulson, Ronny Redlich, Pascal Sienaert, Max L. Stek, Indira Tendolkar, Mathieu Vandenbulcke, Ketil J. Oedegaard, and Anders M. Dale "Volume of the Human Hippocampus and Clinical Response Following Electroconvulsive Therapy" Biological Psychiatry October 15, 2018, 84:574-581 https://doi.org/10.1016/j.biopsych.2018.05.017 Download PDF

B. S. Wade, G. Hellemann, R. T. Espinoza, R. P. Woods, S. H. Joshi, R. Redlich, A. Jørgensen, C. C. Abbott, K. J. Ødegaard, S. M. McClintock, L. Oltedal, and K. Narr, “Depressive Symptom Dimensions in Treatment-Resistant Major Depression and Their Modulation With Electroconvulsive Therapy,” The journal of ECT, 2019. doi:10.1097/YCT.0000000000000623 Download PDF

2018

Leif Oltedal, Katherine L. Narr, Christopher Abbott, Amit Anand, Miklos Argyelan, Hauke Bartsch, Udo Dannlowski, Annemieke Dols, Philip van Eijndhoven, Louise Emsell, Vera Jane Erchinger, Randall Espinoza, Tim Hahn, Lars G. Hanson, Gerhard Hellemann, Martin Balslev Jorgensen, Ute Kessler, Mardien L. Oudega, Olaf B. Paulson, Ronny Redlich, Pascal Sienaert, Max L. Stek, Indira Tendolkar, Mathieu Vandenbulcke, Ketil J. Oedegaard, Anders M. Dale “Volume of the Human Hippocampus and Clinical Response Following Electroconvulsive Therapy,” Biological Psychiatry, vol. 84, iss. 8, pp. 574-581, 2018.https://doi.org/10.1016/j.biopsych.2018.05.017 Download PDF

2017

Leif Oltedal, Hauke Bartsch, Ole Johan Evjenth Sørhaug, Ute Kessler, Christopher Abbott, Annemieke Dols, Max L Stek, Lars Ersland, Louise Emsell, Philip van Eijndhoven, Miklos Argyelan,Indira Tendolkar, Pia Nordanskog, Paul Hamilton, Martin Balslev Jorgensen, Iris E Sommer,Sophie M Heringa, Bogdan Draganski, Ronny Redlich, Udo Dannlowski, Harald Kugel, Filip Bouckaert, Pascal Sienaert, Amit Anand, Randall Espinoza, Katherine L Narr, Dominic Holland, Anders M Dale, Ketil J Oedegaard NeuroImage: Clinical 14 (2017) 422–432 https://doi.org/10.1016/j.nicl.2017.02.009 Download PDF

GEMRIC board members and sites GEMRIC members list

Completed and ongoing analyses in GEMRIC

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