MRCRM seminar series February 2023

Post doc. Sadaf Ghorbani employs brain organoids as an in vitro model of the human brain. This gives a possibility to determine alterations in neuronal processes that are associated with rare variants in schizophrenia and autism disorders.


The prospect of brain 3D models to advance neuropsychiatric research


Brain organoids are laboratory-grown, three-dimensional structures that mimic the cell-type composition and neuronal processes in the human brain. They are becoming increasingly important in the study of psychiatric disorders, as they provide a unique platform for the investigation of brain development and function in a controlled environment.

By using organoids derived from patients with psychiatric disorders, researchers can identify specific molecular and cellular alterations that may contribute to the development of these diseases. Furthermore, organoids can be used to study the mechanism of action for therapeutic interventions or test the efficacy of new therapeutic compounds for various psychiatric disorders, such as depression, schizophrenia, and autism spectrum disorders.

These findings are expected to lead to a better understanding of the underlying causes of psychiatric disorders and to the development of new, more effective treatments.

MRCRM is happy to present our first ever Teams-only monthly seminar, by popular demand! 

If you are not already on our mailing list, please send an email to Titas Gladkauskas or Astrid Bjørke Jenssen to receive an email with invitation to the Teams event. (see contact information)

(We are sadly not able to make this a streaming lecture.)

Portrait of Sadaf Ghorbani. Photo

About the speaker

Sadaf Ghorbani is a Helse Vest postdoc fellow of the Bergen Psychosis group, Helse Bergen. In collaboration with Brennand lab at Yale University, Sadaf aims to develop precision approaches to the treatment of psychiatric disorders

​​Did you find what you were looking for?