Søvn, atferd og luftveisproblemer hos barn født ekstremt premature

Forskere fra Haukeland universitetssykehus, Universitetet i Bergen og Nasjonal kompetansetjeneste for søvnsykdommer ville med denne studien undersøke om ekstremt premature barn med søvnproblemer hadde mer atferds og luftveisproblemer enn ekstremt premature barn uten søvnproblemer. 216 barn i elleveårsalderen, født ekstremt premature, deltok i den spørreskjemabaserte studien hvor foreldrene svarte på om barnet enten hadde problemer med å sovne, hadde hyppige oppvåkninger, snorking, søvnighet på dagtid eller ikke anbefalt søvnlengde (<9 timer). Atferdsproblemer ble vurdert av foreldre og lærere, og foreldrene vurderte luftveissymptomer og beskrev bruk av astmamedisin.

Studien viste at ekstremt premature barn med forskjellige typer søvnproblemer hadde mer atferds- og luftveisproblemer enn ekstremt premature barn uten søvnproblemer.

Sleep problems, behavioural problems and respiratory health in children born extremely preterm: a parental questionnaire study

Kristine Marie Stangenes, Mari Hysing, Irene Bircow Elgen, Thomas Halvorsen, Trond Markestad, Bjørn Bjorvatn

Publisert i British Medical Journal Paediatrics Open

Objective: To explore whether children born extremely preterm (EPT) with different types of sleep problems had more behavioural and respiratory health problems than EPT children without sleep problems.

Design: Prospective, nationwide, questionnaire-based study. At 11 years of age, parents reported on four current sleep problems: difficulty falling asleep or frequent awakenings, snoring, daytime sleepiness and not recommended sleep duration (<9 hours). Behavioural problems were assessed by parents and teachers with the Strengths and Difficulties Questionnaire (SDQ). Parents assessed respiratory symptoms with the International Study of Asthma and Allergies in Childhood questionnaire and described use of asthma medication.

Setting: Norway.

Patients: EPT children.
Main outcome measures: Specified sleep problems, behavioural problems and respiratory health.

Results: Data were obtained from 216 of 372 (58 %) of eligible children. All four specified sleep problems were associated with significantly higher parent-reported SDQ total-score (OR 1.1 for all), and except for not recommended sleep duration,also with higher teacher-reported SDQ total-score (OR 1.1 for all). Daytime sleepiness was strongly associated with wheezing last 12 months (OR 3.4), disturbed sleep due to wheezing (OR 3.9), wheeze during or after exercise (OR 2.9), use of inhaled corticosteroids or oral leukotriene modifiers (OR 3.4) and use of bronchodilators (OR 3.9). Snoring was associated with wheezing during or after exercise (OR 2.8) and current asthma (OR 4.2).

Conclusion: EPT children with different types of sleep problems had more behavioural and respiratory health problems than EPT children without sleep problems