The research projects

The Bergen 4-Day Treatment provides a stringent approach to induce rapid and lasting clinical change, suggesting that the adult brain is capable of plastic changes. As such, the B4DT offers an elegant tool to uncover the mechanisms of brain plasticity in the mature brain with profound implications for understanding numerous psychiatric disorders as well as learning and behaviour in general. 

The partners in BCBP

Bergen Research Foundation, the Kavli TrustHaukeland University Hospital and the University of Bergen have joined forces to establish a new mental health research centre in Bergen, Norway: The Bergen Center for Brain Plasticity.


"The B4DT protocol’s concentrated structure makes it an ideal paradigm to examine how the brain can rapidly learn new emotional processes, says Kerry Ressler, chief scientific officer at McLean Hospital in Massachusetts and one of the scientists involved in this project. Other goals of this work, he adds, include identifying biological markers—in blood, saliva or through neuroimaging—that can pinpoint patients who will best respond to this type of treatment and to gain new insights to help inform future therapies". 

Read the press release from Bergen Research Foundation. For a list of our publications see this page

Brain imaging (fMRI) 

The Bergen 4-day Treatment helps many patients with OCD to recover, but what happens in the brain when they do so? The Bergen Center for Brain Plasticity will study changes in the brain directly after treatment. Brain imaging is performed the day before treatment starts, one week afterwards, and after three months. The combination of concentrated treatment and imaging directly after treatment gives a unique opportunity to help us understand how treatment changes the brain.

Dr. Odile van den Heuvel will together with Dr. Olga Ousdal head the brain imaging project.


You can read more about our biobank in Norwegian.

Treatment studies 

The B4DT is a practical, evidence-based, focused and deliberate exposure based treatment. It builds on four decades of empirical research and theories about the most effective approach to OCD  treatment. The innovation and strength of the work is how it combines the most effective elements of proven treatment into one of the most profound, rapid, and robust treatment approaches that we have seen in recent years.

Recently TIME Magazine selected Gerd Kvale and Bjarne Hansen to be on the list as two of 50 Most Influential People in Health Care for 2018, based on their work with the B4DT . 
Drs. Gerd Kvale and Bjarne Hansen will together with Dr. Thröstur Björgvinsson be heading the psychological parts of the research project, with Dr. Lars-Göran Öst as a core collaborating partner.

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